| pubmed-article:8123625 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8123625 | lifeskim:mentions | umls-concept:C0086427 | lld:lifeskim |
| pubmed-article:8123625 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
| pubmed-article:8123625 | lifeskim:mentions | umls-concept:C0042164 | lld:lifeskim |
| pubmed-article:8123625 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8123625 | pubmed:dateCreated | 1994-4-12 | lld:pubmed |
| pubmed-article:8123625 | pubmed:abstractText | The human retroviruses, HTLV-I and HIV, are playing clinically important roles in a variety of ocular disorders, particularly in uveitis. Both viruses are integrated in the genome of infected T cells. HIV-I infection causes the death of the infected T cells, thereby affecting the host defence system and causing AIDS. Subsequent opportunistic infections of ocular tissues, such as CMV retinitis, are a serious problem in clinical ophthalmology all over the world. Another human retrovirus, HTLV-I, has been known as the causative agent of T cell malignancies (ATL and T cell lymphoma) and chronic myelopathy (HAM/TSP), and is now recognised as a causative agent for a specific type of intraocular inflammation characterised by vitreous opacities with mild iritis and mild retinal vasculitis (HTLV-I uveitis). The mechanism by which HTLV-I causes uveitis is still unknown, but our recent data suggest that it is most probably an immune mediated mechanism by activated CD4 T cells infected with the virus. HTLV-I uveitis, therefore, may implicate a significant role of retroviruses in autoimmune diseases and further the pathogenesis of diseases with infection/autoimmune overlap. | lld:pubmed |
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| pubmed-article:8123625 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8123625 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8123625 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8123625 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8123625 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:8123625 | pubmed:issn | 0007-1161 | lld:pubmed |
| pubmed-article:8123625 | pubmed:author | pubmed-author:WatanabeTT | lld:pubmed |
| pubmed-article:8123625 | pubmed:author | pubmed-author:YamaguchiKK | lld:pubmed |
| pubmed-article:8123625 | pubmed:author | pubmed-author:MochizukiMM | lld:pubmed |
| pubmed-article:8123625 | pubmed:author | pubmed-author:TajimaKK | lld:pubmed |
| pubmed-article:8123625 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8123625 | pubmed:volume | 78 | lld:pubmed |
| pubmed-article:8123625 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8123625 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8123625 | pubmed:pagination | 149-54 | lld:pubmed |
| pubmed-article:8123625 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:8123625 | pubmed:meshHeading | pubmed-meshheading:8123625-... | lld:pubmed |
| pubmed-article:8123625 | pubmed:meshHeading | pubmed-meshheading:8123625-... | lld:pubmed |
| pubmed-article:8123625 | pubmed:meshHeading | pubmed-meshheading:8123625-... | lld:pubmed |
| pubmed-article:8123625 | pubmed:meshHeading | pubmed-meshheading:8123625-... | lld:pubmed |
| pubmed-article:8123625 | pubmed:meshHeading | pubmed-meshheading:8123625-... | lld:pubmed |
| pubmed-article:8123625 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8123625 | pubmed:articleTitle | Human T lymphotropic virus type 1 uveitis. | lld:pubmed |
| pubmed-article:8123625 | pubmed:affiliation | Department of Ophthalmology, Kurume University School of Medicine, Fukuoka, Japan. | lld:pubmed |
| pubmed-article:8123625 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8123625 | pubmed:publicationType | Review | lld:pubmed |
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