| pubmed-article:8112611 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8112611 | lifeskim:mentions | umls-concept:C1414387 | lld:lifeskim |
| pubmed-article:8112611 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:8112611 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:8112611 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:8112611 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:8112611 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8112611 | pubmed:dateCreated | 1994-3-25 | lld:pubmed |
| pubmed-article:8112611 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8112611 | pubmed:abstractText | Using degenerate oligos corresponding to two highly conserved motifs within the protein kinase catalytic domain and a PCR-based cloning strategy, we have isolated a cDNA fragment encoding a new member of the Ser/Thr (serine/threonine) family of protein kinases. Expression analysis revealed that the fragment recognized two transcripts (1.6 and 1.4 kb) exclusively in testis. Using this fragment as a probe, we have cloned a full-length cDNA from a mouse testis cDNA library. The sequence has a 1092-bp open reading frame encoding a protein of 364 amino acids. The N-terminally localized kinase catalytic domain has all the conserved motifs found in other Ser/Thr kinases. Northern blot analysis using the full-length sequence as a probe revealed that the cloned gene corresponds to the 1.6-kb transcript, suggesting the existence of at least two testis-specific novel Ser/Thr kinases. We propose the name testis-specific kinase-1 (TSK-1) for the gene described here. A GenEMBL databank search revealed highest homology to the human gene encoding rac protein kinase-beta and the group of yeast Ser/Thr kinases encoded by SNF-1, nim-1, KIN-1 and KIN-2. | lld:pubmed |
| pubmed-article:8112611 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8112611 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8112611 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8112611 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8112611 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8112611 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:8112611 | pubmed:issn | 0378-1119 | lld:pubmed |
| pubmed-article:8112611 | pubmed:author | pubmed-author:ZürcherGG | lld:pubmed |
| pubmed-article:8112611 | pubmed:author | pubmed-author:ZiemieckiAA | lld:pubmed |
| pubmed-article:8112611 | pubmed:author | pubmed-author:AndresA CAC | lld:pubmed |
| pubmed-article:8112611 | pubmed:author | pubmed-author:MiescherG CGC | lld:pubmed |
| pubmed-article:8112611 | pubmed:author | pubmed-author:BielkeWW | lld:pubmed |
| pubmed-article:8112611 | pubmed:author | pubmed-author:BlaschkeR JRJ | lld:pubmed |
| pubmed-article:8112611 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8112611 | pubmed:day | 25 | lld:pubmed |
| pubmed-article:8112611 | pubmed:volume | 139 | lld:pubmed |
| pubmed-article:8112611 | pubmed:geneSymbol | TSK-1 | lld:pubmed |
| pubmed-article:8112611 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8112611 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8112611 | pubmed:pagination | 235-9 | lld:pubmed |
| pubmed-article:8112611 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:meshHeading | pubmed-meshheading:8112611-... | lld:pubmed |
| pubmed-article:8112611 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8112611 | pubmed:articleTitle | Characterization of a novel murine testis-specific serine/threonine kinase. | lld:pubmed |
| pubmed-article:8112611 | pubmed:affiliation | Laboratory for Clinical and Experimental Research, University of Berne, Switzerland. | lld:pubmed |
| pubmed-article:8112611 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8112611 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:22114 | entrezgene:pubmed | pubmed-article:8112611 | lld:entrezgene |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8112611 | lld:pubmed |
