| pubmed-article:8094730 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8094730 | lifeskim:mentions | umls-concept:C0043167 | lld:lifeskim |
| pubmed-article:8094730 | lifeskim:mentions | umls-concept:C0021270 | lld:lifeskim |
| pubmed-article:8094730 | lifeskim:mentions | umls-concept:C0018850 | lld:lifeskim |
| pubmed-article:8094730 | lifeskim:mentions | umls-concept:C1519885 | lld:lifeskim |
| pubmed-article:8094730 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:8094730 | pubmed:dateCreated | 1993-3-24 | lld:pubmed |
| pubmed-article:8094730 | pubmed:abstractText | To investigate whether and in which proportion normal individuals experience a priming to microbial heat shock proteins (hsp), the presence of antibodies to two mycobacterial hsp was tested in serum sample from 2- to 4-mo-old children before and at different times after vaccination with the trivalent vaccine against tetanus, diphtheria, and pertussis (DTP). We show that 88.9% of infants vaccinated with DTP developed antibody responses to mycobacterial hsp. Such a response was due to the whole-cell pertussis component of the vaccine, because it was not observed in infants receiving an acellular pertussis vaccine. Antibodies and cells reactive to the mycobacterial 65-kDa hsp were also found in mice immunized with DTP. Interestingly, whole-cell pertussis vaccine-induced anti-hsp antibodies cross-reacted with the Escherichia coli GroEL hsp, and at a some extent with the human 60-kDa hsp, belonging to the same hsp family. These data suggest that priming of the immune system to hsp is a common phenomenon occurring very early in life. | lld:pubmed |
| pubmed-article:8094730 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8094730 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8094730 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:8094730 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8094730 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:8094730 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:8094730 | pubmed:author | pubmed-author:GervaisFF | lld:pubmed |
| pubmed-article:8094730 | pubmed:author | pubmed-author:van EmbdenJJ | lld:pubmed |
| pubmed-article:8094730 | pubmed:author | pubmed-author:van der ZeeRR | lld:pubmed |
| pubmed-article:8094730 | pubmed:author | pubmed-author:CostantinoPP | lld:pubmed |
| pubmed-article:8094730 | pubmed:author | pubmed-author:RappuoliRR | lld:pubmed |
| pubmed-article:8094730 | pubmed:author | pubmed-author:de... | lld:pubmed |
| pubmed-article:8094730 | pubmed:author | pubmed-author:Del GiudiceGG | lld:pubmed |
| pubmed-article:8094730 | pubmed:author | pubmed-author:NencioniLL | lld:pubmed |
| pubmed-article:8094730 | pubmed:author | pubmed-author:TougneCC | lld:pubmed |
| pubmed-article:8094730 | pubmed:author | pubmed-author:WylerC ACA | lld:pubmed |
| pubmed-article:8094730 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8094730 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:8094730 | pubmed:volume | 150 | lld:pubmed |
| pubmed-article:8094730 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8094730 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:8094730 | pubmed:pagination | 2025-32 | lld:pubmed |
| pubmed-article:8094730 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:8094730 | pubmed:meshHeading | pubmed-meshheading:8094730-... | lld:pubmed |
| pubmed-article:8094730 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8094730 | pubmed:articleTitle | Priming to heat shock proteins in infants vaccinated against pertussis. | lld:pubmed |
| pubmed-article:8094730 | pubmed:affiliation | Department of Pathology, University of Geneva, Switzerland. | lld:pubmed |
| pubmed-article:8094730 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8094730 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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