| pubmed-article:8084545 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8084545 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:8084545 | lifeskim:mentions | umls-concept:C0001811 | lld:lifeskim |
| pubmed-article:8084545 | lifeskim:mentions | umls-concept:C0002395 | lld:lifeskim |
| pubmed-article:8084545 | lifeskim:mentions | umls-concept:C0020179 | lld:lifeskim |
| pubmed-article:8084545 | lifeskim:mentions | umls-concept:C0682708 | lld:lifeskim |
| pubmed-article:8084545 | lifeskim:mentions | umls-concept:C0016733 | lld:lifeskim |
| pubmed-article:8084545 | lifeskim:mentions | umls-concept:C0140080 | lld:lifeskim |
| pubmed-article:8084545 | lifeskim:mentions | umls-concept:C0599283 | lld:lifeskim |
| pubmed-article:8084545 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:8084545 | pubmed:dateCreated | 1994-10-11 | lld:pubmed |
| pubmed-article:8084545 | pubmed:abstractText | Using quantitative autoradiography we have investigated insulin-like growth factor (IGF)-I receptors in postmortem-obtained frontal cortex and white matter from 39 individuals without neurological disease, ranging in age from 0 to 95 years, and from 5 patients with Huntington's disease and 4 with Alzheimer's disease. IGF-I receptor densities in white matter were significantly higher in neonates than in adults; during adult life there was no further decline. The higher density of IGF-I receptors in white matter of neonates most likely reflects extensive formation of myelin. There was no significant decrease in IGF-I receptor densities in the cortical mantle with age, suggesting that the cells containing IGF-I receptors in frontal cortex are maintained during the entire life-span. There were no significant alterations in IGF-I receptor densities in frontal cortex and white matter from patients with Huntington's disease and Alzheimer's disease compared with controls from the same age groups. | lld:pubmed |
| pubmed-article:8084545 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8084545 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8084545 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8084545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8084545 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8084545 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8084545 | pubmed:month | May | lld:pubmed |
| pubmed-article:8084545 | pubmed:issn | 0304-3940 | lld:pubmed |
| pubmed-article:8084545 | pubmed:author | pubmed-author:De KeyserJJ | lld:pubmed |
| pubmed-article:8084545 | pubmed:author | pubmed-author:GoossensAA | lld:pubmed |
| pubmed-article:8084545 | pubmed:author | pubmed-author:WilczakNN | lld:pubmed |
| pubmed-article:8084545 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8084545 | pubmed:day | 19 | lld:pubmed |
| pubmed-article:8084545 | pubmed:volume | 172 | lld:pubmed |
| pubmed-article:8084545 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8084545 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8084545 | pubmed:pagination | 93-6 | lld:pubmed |
| pubmed-article:8084545 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:meshHeading | pubmed-meshheading:8084545-... | lld:pubmed |
| pubmed-article:8084545 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8084545 | pubmed:articleTitle | Insulin-like growth factor-I receptor densities in human frontal cortex and white matter during aging, in Alzheimer's disease, and in Huntington's disease. | lld:pubmed |
| pubmed-article:8084545 | pubmed:affiliation | Department of Neurology, Academisch Ziekenhuis, Vrije Universiteit Brussel, Belgium. | lld:pubmed |
| pubmed-article:8084545 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8084545 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
