| pubmed-article:80835 | pubmed:abstractText | The proliferative response of normal lymph node cells from different mouse strains to an Abelson virus-induced leukemic cell line (MLVA) in mixed leukocyte culture (MLC) has been investigated. MLVA leukemic cells do stimulate a specific response and the stimulating determinants are controlled, most likely, by genes in the K-end of the H--2 complex. However, using two different anti-Ia sera and different assay systems, we were unable to detect the expression of Ia-antigens on MLVA. In addition, an alloantiserum raised against MLVA, and absorbed with P815, a nonstimulating mastocytoma cell line, showed no residual activity against MLVA cells. | lld:pubmed |
