pubmed-article:8026540 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8026540 | lifeskim:mentions | umls-concept:C1135918 | lld:lifeskim |
pubmed-article:8026540 | lifeskim:mentions | umls-concept:C0021853 | lld:lifeskim |
pubmed-article:8026540 | lifeskim:mentions | umls-concept:C0010737 | lld:lifeskim |
pubmed-article:8026540 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:8026540 | pubmed:issue | 1-3 | lld:pubmed |
pubmed-article:8026540 | pubmed:dateCreated | 1994-8-8 | lld:pubmed |
pubmed-article:8026540 | pubmed:abstractText | The inhibitory effect of cytochalasin B on contraction of smooth muscle cells isolated from guinea-pig taenia coli was investigated. Cytochalasin B (10-70 microM) inhibited the high K+ (70 mM)-induced contraction in a dose-dependent manner, and the maximum and the half-maximum effects were obtained at 50 and 15 microM, respectively. Cytochalasin B (70 microM) decreased ATPase activity in skinned guinea-pig taenia coli. However, cytochalasin B (50 microM) had no significant effect on the voltage-dependent Ca2+ currents, the passive membrane properties or the membrane potential. Cytochalasin B also had no effect on the phosphorylation of 20 kDa myosin light chain induced by high K+ and cytosolic Ca2+ levels. These results suggest that the inhibition of contraction by cytochalasin B may be due to its effects on actin of microfilaments and contractile filaments of guinea-pig taenia coli smooth muscle cells. | lld:pubmed |
pubmed-article:8026540 | pubmed:language | eng | lld:pubmed |
pubmed-article:8026540 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8026540 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8026540 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8026540 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8026540 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8026540 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8026540 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8026540 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8026540 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8026540 | pubmed:month | Apr | lld:pubmed |
pubmed-article:8026540 | pubmed:issn | 0014-2999 | lld:pubmed |
pubmed-article:8026540 | pubmed:author | pubmed-author:YabuHH | lld:pubmed |
pubmed-article:8026540 | pubmed:author | pubmed-author:ObaraKK | lld:pubmed |
pubmed-article:8026540 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8026540 | pubmed:day | 1 | lld:pubmed |
pubmed-article:8026540 | pubmed:volume | 255 | lld:pubmed |
pubmed-article:8026540 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8026540 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8026540 | pubmed:pagination | 139-47 | lld:pubmed |
pubmed-article:8026540 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:8026540 | pubmed:year | 1994 | lld:pubmed |
pubmed-article:8026540 | pubmed:articleTitle | Effect of cytochalasin B on intestinal smooth muscle cells. | lld:pubmed |
pubmed-article:8026540 | pubmed:affiliation | Department of Physiology, School of Medicine, Sapporo Medical University, Japan. | lld:pubmed |
pubmed-article:8026540 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8026540 | pubmed:publicationType | In Vitro | lld:pubmed |
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