| pubmed-article:8023637 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8023637 | lifeskim:mentions | umls-concept:C2752508 | lld:lifeskim |
| pubmed-article:8023637 | lifeskim:mentions | umls-concept:C1167322 | lld:lifeskim |
| pubmed-article:8023637 | lifeskim:mentions | umls-concept:C0916181 | lld:lifeskim |
| pubmed-article:8023637 | lifeskim:mentions | umls-concept:C0812409 | lld:lifeskim |
| pubmed-article:8023637 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
| pubmed-article:8023637 | lifeskim:mentions | umls-concept:C1709059 | lld:lifeskim |
| pubmed-article:8023637 | lifeskim:mentions | umls-concept:C0037791 | lld:lifeskim |
| pubmed-article:8023637 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:8023637 | pubmed:dateCreated | 1994-8-4 | lld:pubmed |
| pubmed-article:8023637 | pubmed:abstractText | We have previously reported that transmembrane Ca2+ gradient-mediated changes in lipid fluidity could modulate the conformation and enzyme activity of sarcoplasmic reticulum (SR) Ca(2+)-ATPase. The aim of this paper is to explore the specificity of transmembrane Ca2+ gradient-mediated modulation of SR Ca(2+)-ATPase. The results showed that such specificity exhibited in two aspects: 1. The modulation could not be ascribed to transmembrane potential resulted from the transmembrane Ca2+ gradient, Dissipation of transmembrane potential by FCCP (carbonylcyanide-p-trifluoromethoxyphenylhydrazone) could not affect the activity of SR Ca(2+)-ATPase. 2. Transmembrane Sr2+ gradient had little effect on the enzyme activity of SR Ca(2+)-ATPase. A significant difference between the effect of transmembrane Ca2+ and Sr2+ gradient on the lipid fluidity was detected in the middle region of bilayer of Ca(2+)-ATPase incorporated proteoliposomes using a set of n-AS [n-(9-anthroyloxy) fatty acids] fluorescence polarization probes. It is known that Ca2+ binding domain of SR Ca(2+)-ATPase is just located in the middle region of bilayer, hence it may be deduced that possibly, membrane lipids are involved in transmembrane Ca2+ gradient-mediated modulation of Ca(2+)-ATPase. | lld:pubmed |
| pubmed-article:8023637 | pubmed:language | chi | lld:pubmed |
| pubmed-article:8023637 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8023637 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8023637 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8023637 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8023637 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8023637 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8023637 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8023637 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8023637 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:8023637 | pubmed:issn | 0001-5334 | lld:pubmed |
| pubmed-article:8023637 | pubmed:author | pubmed-author:XuHH | lld:pubmed |
| pubmed-article:8023637 | pubmed:author | pubmed-author:YangF YFY | lld:pubmed |
| pubmed-article:8023637 | pubmed:author | pubmed-author:TuY PYP | lld:pubmed |
| pubmed-article:8023637 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8023637 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:8023637 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8023637 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8023637 | pubmed:pagination | 441-7 | lld:pubmed |
| pubmed-article:8023637 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:8023637 | pubmed:meshHeading | pubmed-meshheading:8023637-... | lld:pubmed |
| pubmed-article:8023637 | pubmed:meshHeading | pubmed-meshheading:8023637-... | lld:pubmed |
| pubmed-article:8023637 | pubmed:meshHeading | pubmed-meshheading:8023637-... | lld:pubmed |
| pubmed-article:8023637 | pubmed:meshHeading | pubmed-meshheading:8023637-... | lld:pubmed |
| pubmed-article:8023637 | pubmed:meshHeading | pubmed-meshheading:8023637-... | lld:pubmed |
| pubmed-article:8023637 | pubmed:meshHeading | pubmed-meshheading:8023637-... | lld:pubmed |
| pubmed-article:8023637 | pubmed:meshHeading | pubmed-meshheading:8023637-... | lld:pubmed |
| pubmed-article:8023637 | pubmed:meshHeading | pubmed-meshheading:8023637-... | lld:pubmed |
| pubmed-article:8023637 | pubmed:meshHeading | pubmed-meshheading:8023637-... | lld:pubmed |
| pubmed-article:8023637 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8023637 | pubmed:articleTitle | [The specificity of modulation of sarcoplasmic reticulum Ca(2+)-ATPase by transmembrane Ca2+ gradient]. | lld:pubmed |
| pubmed-article:8023637 | pubmed:affiliation | National Laboratory of Biomacromolecules, Institute of Biophysics, Academia Sinica, Beijing, China. | lld:pubmed |
| pubmed-article:8023637 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8023637 | pubmed:publicationType | English Abstract | lld:pubmed |
| pubmed-article:8023637 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
