pubmed-article:7894265 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7894265 | lifeskim:mentions | umls-concept:C0013227 | lld:lifeskim |
pubmed-article:7894265 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:7894265 | lifeskim:mentions | umls-concept:C0007776 | lld:lifeskim |
pubmed-article:7894265 | lifeskim:mentions | umls-concept:C0022655 | lld:lifeskim |
pubmed-article:7894265 | lifeskim:mentions | umls-concept:C0001613 | lld:lifeskim |
pubmed-article:7894265 | lifeskim:mentions | umls-concept:C1166795 | lld:lifeskim |
pubmed-article:7894265 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:7894265 | lifeskim:mentions | umls-concept:C2003941 | lld:lifeskim |
pubmed-article:7894265 | lifeskim:mentions | umls-concept:C0598352 | lld:lifeskim |
pubmed-article:7894265 | lifeskim:mentions | umls-concept:C2700116 | lld:lifeskim |
pubmed-article:7894265 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:7894265 | pubmed:dateCreated | 1995-4-27 | lld:pubmed |
pubmed-article:7894265 | pubmed:abstractText | The dose-response curves for a number of alpha-adrenergic drugs were investigated to estimate a possible role of the alpha 2/alpha 1 selectivity of these drugs on the incidence of cortical high voltage spindles (HVS), reflecting level of vigilance. The alpha 2 antagonists yohimbine (0.25-4 mg/kg) and idazoxan (0.5-4 mg/kg), but not atipamezole induced a biphasic effect on the incidence of HVS in rats. This effect of relatively small doses of yohimbine and idazoxan should be taken into consideration when using these drugs as alpha 2 antagonists in behavioral and neurophysiological tests. On the other hand the linearity of the dose-response curve for atipamezole (0.01-4 mg/kg) indicates that this drug is a good candidate for use in such tests. | lld:pubmed |
pubmed-article:7894265 | pubmed:language | eng | lld:pubmed |
pubmed-article:7894265 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7894265 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:7894265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7894265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7894265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7894265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7894265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7894265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7894265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7894265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7894265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7894265 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7894265 | pubmed:month | Dec | lld:pubmed |
pubmed-article:7894265 | pubmed:issn | 0924-977X | lld:pubmed |
pubmed-article:7894265 | pubmed:author | pubmed-author:SirviöJJ | lld:pubmed |
pubmed-article:7894265 | pubmed:author | pubmed-author:RiekkinenPPSr | lld:pubmed |
pubmed-article:7894265 | pubmed:author | pubmed-author:HaapalinnaAA | lld:pubmed |
pubmed-article:7894265 | pubmed:author | pubmed-author:YavichLL | lld:pubmed |
pubmed-article:7894265 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7894265 | pubmed:volume | 4 | lld:pubmed |
pubmed-article:7894265 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7894265 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7894265 | pubmed:pagination | 535-8 | lld:pubmed |
pubmed-article:7894265 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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pubmed-article:7894265 | pubmed:year | 1994 | lld:pubmed |
pubmed-article:7894265 | pubmed:articleTitle | Some unusual effects of alpha 2-adrenergic drugs on cortical high voltage spindles in rats. | lld:pubmed |
pubmed-article:7894265 | pubmed:affiliation | Department of Neurology, University of Kuopio, Finland. | lld:pubmed |
pubmed-article:7894265 | pubmed:publicationType | Journal Article | lld:pubmed |