| pubmed-article:7811740 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7811740 | lifeskim:mentions | umls-concept:C0009015 | lld:lifeskim |
| pubmed-article:7811740 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
| pubmed-article:7811740 | lifeskim:mentions | umls-concept:C0023837 | lld:lifeskim |
| pubmed-article:7811740 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:7811740 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:7811740 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:7811740 | pubmed:dateCreated | 1995-2-9 | lld:pubmed |
| pubmed-article:7811740 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7811740 | pubmed:abstractText | We have isolated a murine macrophage cDNA encoding a 12-lipoxygenase, that represents the homolog of the human 15-lipoxygenase. The predicted amino acid sequence of this lipoxygenase is highly similar to the rat 12-lipoxygenase isolated from brain and human 15-lipoxgenase. The recombinant enzyme expressed in Cos-7 cells oxidizes arachidonic acid to 12- and 15-HETE with a profile similar to that obtained from peritoneal macrophages. A polyclonal antibody generated against a putative peptide recognizes a 75 kDa protein in cell extracts from mouse peritoneal macrophages and transfected Cos-7 cells. The lipoxygenase cDNA hybridizes to a 2.5 kb mRNA present in peritoneal macrophages, lung, spleen, heart and liver. RT-PCR analysis indicates that the same lipoxygenase is expressed in mouse reticulocytes. A partial genomic clone for this lipoxygenase has also been characterized. Southern blot analysis of mouse genomic DNA indicates that this is a single copy gene. | lld:pubmed |
| pubmed-article:7811740 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7811740 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7811740 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7811740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7811740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7811740 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7811740 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:7811740 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:7811740 | pubmed:author | pubmed-author:MulkinsMM | lld:pubmed |
| pubmed-article:7811740 | pubmed:author | pubmed-author:OINN | lld:pubmed |
| pubmed-article:7811740 | pubmed:author | pubmed-author:Freire-MoarJJ | lld:pubmed |
| pubmed-article:7811740 | pubmed:author | pubmed-author:SigalEE | lld:pubmed |
| pubmed-article:7811740 | pubmed:author | pubmed-author:Alavi-NassabA... | lld:pubmed |
| pubmed-article:7811740 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7811740 | pubmed:day | 3 | lld:pubmed |
| pubmed-article:7811740 | pubmed:volume | 1254 | lld:pubmed |
| pubmed-article:7811740 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7811740 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7811740 | pubmed:pagination | 112-6 | lld:pubmed |
| pubmed-article:7811740 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:meshHeading | pubmed-meshheading:7811740-... | lld:pubmed |
| pubmed-article:7811740 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7811740 | pubmed:articleTitle | Cloning and characterization of a murine macrophage lipoxygenase. | lld:pubmed |
| pubmed-article:7811740 | pubmed:affiliation | Syntex Discovery Research, Department of Inflammation Biology and Immunology, Palo Alto, CA 94304. | lld:pubmed |
| pubmed-article:7811740 | pubmed:publicationType | Journal Article | lld:pubmed |
| entrez-gene:11687 | entrezgene:pubmed | pubmed-article:7811740 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7811740 | lld:pubmed |
