| pubmed-article:7722170 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7722170 | lifeskim:mentions | umls-concept:C0021051 | lld:lifeskim |
| pubmed-article:7722170 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:7722170 | lifeskim:mentions | umls-concept:C0012634 | lld:lifeskim |
| pubmed-article:7722170 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:7722170 | lifeskim:mentions | umls-concept:C0392209 | lld:lifeskim |
| pubmed-article:7722170 | lifeskim:mentions | umls-concept:C0236175 | lld:lifeskim |
| pubmed-article:7722170 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
| pubmed-article:7722170 | lifeskim:mentions | umls-concept:C0439662 | lld:lifeskim |
| pubmed-article:7722170 | lifeskim:mentions | umls-concept:C0549193 | lld:lifeskim |
| pubmed-article:7722170 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:7722170 | pubmed:dateCreated | 1995-5-24 | lld:pubmed |
| pubmed-article:7722170 | pubmed:abstractText | Elevation of IgE has been associated with T-cell dysregulation and with the occurrence of opportunistic infections in patients with acquired immunodeficiency syndrome. The precise cause of IgE overproduction during the early stages of human immunodeficiency virus (HIV)-1 disease, however, has not been established. In light of reports demonstrating that IgE production may be affected by vitamin E levels in an animal model, we evaluated nutritional status in relationship to plasma IgE levels and immune parameters in 100 asymptomatic HIV-1-seropositive and 42 HIV-1-seronegative homosexual men. Approximately 18% of the HIV-1-seropositive population demonstrated biochemical evidence of plasma vitamin E deficiency (< 5 micrograms/ml). Subsequent analysis of available samples indicated a dramatic elevation of IgE levels (308 +/- 112 IU/ml) in vitamin E-deficient seropositive subjects (n = 9) as compared with age and CD4-matched HIV-1-seropositive persons with adequate vitamin E levels (n = 16, 118.1 +/- 41.1 IU/ml) and significantly lower levels (59.5 +/- 15.7 IU/ml) in HIV-1-seronegative men (n = 20, p = 0.01). This effect, which was independent of CD4 cell count, did not appear to be influenced by atopic or gastrointestinal parasitic disease. The low plasma vitamin E levels were related at least in part to dietary intake (r = 0.552, p = 0.01), suggesting that supplementation may be warranted in HIV-1-infected persons in whom vitamin E deficiency develops. Analysis of covariance revealed a strong relationship between IgE levels and CD8 cell counts (p < 0.006), and between IgE level and vitamin E deficiency (p < 0.039).(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:7722170 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7722170 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7722170 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7722170 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7722170 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:7722170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7722170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7722170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7722170 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7722170 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:7722170 | pubmed:issn | 0091-6749 | lld:pubmed |
| pubmed-article:7722170 | pubmed:author | pubmed-author:SauberlichHH | lld:pubmed |
| pubmed-article:7722170 | pubmed:author | pubmed-author:LoSS | lld:pubmed |
| pubmed-article:7722170 | pubmed:author | pubmed-author:FletcherMM | lld:pubmed |
| pubmed-article:7722170 | pubmed:author | pubmed-author:BUCAJ TJT | lld:pubmed |
| pubmed-article:7722170 | pubmed:author | pubmed-author:Shor-PosnerGG | lld:pubmed |
| pubmed-article:7722170 | pubmed:author | pubmed-author:FeasterDD | lld:pubmed |
| pubmed-article:7722170 | pubmed:author | pubmed-author:Miguez-Burban... | lld:pubmed |
| pubmed-article:7722170 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7722170 | pubmed:volume | 95 | lld:pubmed |
| pubmed-article:7722170 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7722170 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7722170 | pubmed:pagination | 886-92 | lld:pubmed |
| pubmed-article:7722170 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:7722170 | pubmed:meshHeading | pubmed-meshheading:7722170-... | lld:pubmed |
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| pubmed-article:7722170 | pubmed:meshHeading | pubmed-meshheading:7722170-... | lld:pubmed |
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| pubmed-article:7722170 | pubmed:meshHeading | pubmed-meshheading:7722170-... | lld:pubmed |
| pubmed-article:7722170 | pubmed:meshHeading | pubmed-meshheading:7722170-... | lld:pubmed |
| pubmed-article:7722170 | pubmed:meshHeading | pubmed-meshheading:7722170-... | lld:pubmed |
| pubmed-article:7722170 | pubmed:meshHeading | pubmed-meshheading:7722170-... | lld:pubmed |
| pubmed-article:7722170 | pubmed:meshHeading | pubmed-meshheading:7722170-... | lld:pubmed |
| pubmed-article:7722170 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7722170 | pubmed:articleTitle | Elevated IgE level in relationship to nutritional status and immune parameters in early human immunodeficiency virus-1 disease. | lld:pubmed |
| pubmed-article:7722170 | pubmed:affiliation | Department of Epidemiology and Public Health, University of Miami School of Medicine, FL 33101, USA. | lld:pubmed |
| pubmed-article:7722170 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7722170 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7722170 | lld:pubmed |
