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pubmed-article:7699717pubmed:abstractTextWe have prepared a [32P]-labeled oligonucleotide probe carrying a ureido (-NH-CO-NH2) function at its 3'-terminus. This labeled oligomer was used to study polycondensations of urea and formaldehyde and of various phenols and formaldehyde in aqueous solution. The formation of formaldehyde copolymers attached to the amido-function of the probe was monitored by gel electrophoresis. Our results are generally in agreement with those obtained using conventional techniques. Our method is suitable for monitoring potentially prebiotic polycondensation reactions involving formaldehyde.lld:pubmed
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pubmed-article:7699717pubmed:pagination115-9lld:pubmed
pubmed-article:7699717pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:7699717pubmed:articleTitleOligonucleotides as probes for studying polymerization reactions in dilute aqueous solution: II. Polycondensations.lld:pubmed
pubmed-article:7699717pubmed:affiliationSalk Institute for Biological Studies, San Diego, CA 92186-5800.lld:pubmed
pubmed-article:7699717pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:7699717pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed