| pubmed-article:7691798 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7691798 | lifeskim:mentions | umls-concept:C1257748 | lld:lifeskim |
| pubmed-article:7691798 | lifeskim:mentions | umls-concept:C0035028 | lld:lifeskim |
| pubmed-article:7691798 | pubmed:issue | 20 | lld:pubmed |
| pubmed-article:7691798 | pubmed:dateCreated | 1993-11-19 | lld:pubmed |
| pubmed-article:7691798 | pubmed:abstractText | Accumulation of stable RNA and production of guanosine polyphosphates (ppGpp and pppGpp) were studied during amino acid starvation in four species of halobacteria. In two of the four species, stable RNA was under stringent control, whereas one of the remaining two species was relaxed and the other gave an intermediate phenotype. The stringent reaction was reversed by anisomycin, an effect analogous to the chloroamphenicol-induced reversal of stringency in the eubacteria. During the stringent response, neither ppGpp nor pppGpp accumulation took place during starvation. In both growing and starved cells a very low basal level of the two polyphosphates appeared to be present. In the stringent species the intracellular concentration of GTP did not diminish but actually increased during the course of the stringent response. These data demonstrate that (i) wild-type halobacteria can have either the stringent or the relaxed phenotype (all wild-type eubacteria tested have been shown to be stringent); (ii) stringency in the halobacteria is dependent on the deaminoacylation of tRNA, as in the eubacteria; and (iii) in the halobacteria, ppGpp is not an effector of stringent control over stable-RNA synthesis. | lld:pubmed |
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| pubmed-article:7691798 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7691798 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7691798 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:7691798 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7691798 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:7691798 | pubmed:issn | 0021-9193 | lld:pubmed |
| pubmed-article:7691798 | pubmed:author | pubmed-author:DoniniPP | lld:pubmed |
| pubmed-article:7691798 | pubmed:author | pubmed-author:CimminoCC | lld:pubmed |
| pubmed-article:7691798 | pubmed:author | pubmed-author:ScoarughiG... | lld:pubmed |
| pubmed-article:7691798 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7691798 | pubmed:volume | 175 | lld:pubmed |
| pubmed-article:7691798 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7691798 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7691798 | pubmed:pagination | 6659-62 | lld:pubmed |
| pubmed-article:7691798 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:7691798 | pubmed:meshHeading | pubmed-meshheading:7691798-... | lld:pubmed |
| pubmed-article:7691798 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:7691798 | pubmed:articleTitle | Stringency and relaxation among the halobacteria. | lld:pubmed |
| pubmed-article:7691798 | pubmed:affiliation | Dipartimento di Biologia Cellulare e dello Sviluppo, Università, La Sapienza, Rome, Italy. | lld:pubmed |
| pubmed-article:7691798 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7691798 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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