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pubmed-article:7685831pubmed:abstractTextPrevious studies indicate that the heparinoid pentosan polysulfate (PPS) can inhibit heparin-binding growth factors (HBGFs) released from tumor cells and thus block tumor growth in animal models. However, because of its heparin-like activity, the major toxic effect expected for PPS is its inhibition of coagulation.lld:pubmed
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pubmed-article:7685831pubmed:articleTitleDetectable inhibition of heparin-binding growth factor activity in sera from patients treated with pentosan polysulfate.lld:pubmed
pubmed-article:7685831pubmed:affiliationV.T. Lombardi Cancer Research Center, Georgetown University Medical Center, Washington, D.C. 20007.lld:pubmed
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