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pubmed-article:7673026pubmed:abstractTextRecent clinical investigations have shown a strong correlation between pretreatment tumor hypoxia and poor response to radiotherapy. These observations raise questions about standard assumptions of tumor reoxygenation during radiotherapy, which has been poorly studied in human cancers. Positron emission tomography (PET) imaging of [F-18]fluoromisonidazole (FMISO) uptake allows noninvasive assessment of tumor hypoxia, and is amenable for repeated studies during fractionated radiotherapy to systematically evaluate changes in tumor oxygenation.lld:pubmed
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pubmed-article:7673026pubmed:articleTitleEvaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography.lld:pubmed
pubmed-article:7673026pubmed:affiliationDepartment of Radiation Oncology, University of Washington School of Medicine, Seattle, USA.lld:pubmed
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