| pubmed-article:7667387 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7667387 | lifeskim:mentions | umls-concept:C0001792 | lld:lifeskim |
| pubmed-article:7667387 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:7667387 | lifeskim:mentions | umls-concept:C0233794 | lld:lifeskim |
| pubmed-article:7667387 | lifeskim:mentions | umls-concept:C0243192 | lld:lifeskim |
| pubmed-article:7667387 | lifeskim:mentions | umls-concept:C1555029 | lld:lifeskim |
| pubmed-article:7667387 | lifeskim:mentions | umls-concept:C0332185 | lld:lifeskim |
| pubmed-article:7667387 | lifeskim:mentions | umls-concept:C0205923 | lld:lifeskim |
| pubmed-article:7667387 | lifeskim:mentions | umls-concept:C0073475 | lld:lifeskim |
| pubmed-article:7667387 | pubmed:issue | 2-3 | lld:pubmed |
| pubmed-article:7667387 | pubmed:dateCreated | 1995-10-11 | lld:pubmed |
| pubmed-article:7667387 | pubmed:abstractText | The benzodiazepine receptor partial inverse agonist RO 15-3505 was tested for its ability to improve impaired recent memory of aged mice. All mice successfully acquired a learning set for accurate identification of the correct arm of a T-maze and could perform with nearly 100% accuracy after 1-min delays. However, performance of the aged mice approached chance levels after 2-h delays. When injected just before testing on a series of 2-h retention tests, RO 15-3505 (from 2.5-3505 (from 2.5-10.0 mg/kg) resulted in a marked improvement of response accuracy. These results confirm the role of benzodiazepine receptor mechanisms in the modulation of memory processes, and suggest that the memory-facilitating effects RO 15-3505 or similar benzodiazepine receptor ligands may be generalized to aged rodents with impaired memory function. | lld:pubmed |
| pubmed-article:7667387 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7667387 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7667387 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7667387 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7667387 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7667387 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7667387 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7667387 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7667387 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7667387 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7667387 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7667387 | pubmed:issn | 0091-3057 | lld:pubmed |
| pubmed-article:7667387 | pubmed:author | pubmed-author:MAS | lld:pubmed |
| pubmed-article:7667387 | pubmed:author | pubmed-author:PatelS RSR | lld:pubmed |
| pubmed-article:7667387 | pubmed:author | pubmed-author:PratherP LPL | lld:pubmed |
| pubmed-article:7667387 | pubmed:author | pubmed-author:ForsterM JMJ | lld:pubmed |
| pubmed-article:7667387 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7667387 | pubmed:volume | 51 | lld:pubmed |
| pubmed-article:7667387 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7667387 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7667387 | pubmed:pagination | 557-60 | lld:pubmed |
| pubmed-article:7667387 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:7667387 | pubmed:meshHeading | pubmed-meshheading:7667387-... | lld:pubmed |
| pubmed-article:7667387 | pubmed:meshHeading | pubmed-meshheading:7667387-... | lld:pubmed |
| pubmed-article:7667387 | pubmed:meshHeading | pubmed-meshheading:7667387-... | lld:pubmed |
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| pubmed-article:7667387 | pubmed:meshHeading | pubmed-meshheading:7667387-... | lld:pubmed |
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| pubmed-article:7667387 | pubmed:meshHeading | pubmed-meshheading:7667387-... | lld:pubmed |
| pubmed-article:7667387 | pubmed:meshHeading | pubmed-meshheading:7667387-... | lld:pubmed |
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| pubmed-article:7667387 | pubmed:meshHeading | pubmed-meshheading:7667387-... | lld:pubmed |
| pubmed-article:7667387 | pubmed:articleTitle | The benzodiazepine receptor inverse agonist RO 15-3505 reverses recent memory deficits in aged mice. | lld:pubmed |
| pubmed-article:7667387 | pubmed:affiliation | Department of Pharmacology, University of North Texas Health Science Center at Fort Worth 76107-2699, USA. | lld:pubmed |
| pubmed-article:7667387 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7667387 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7667387 | lld:pubmed |
