| pubmed-article:7660441 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7660441 | lifeskim:mentions | umls-concept:C0024535 | lld:lifeskim |
| pubmed-article:7660441 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:7660441 | lifeskim:mentions | umls-concept:C2003941 | lld:lifeskim |
| pubmed-article:7660441 | lifeskim:mentions | umls-concept:C1280519 | lld:lifeskim |
| pubmed-article:7660441 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:7660441 | pubmed:dateCreated | 1995-10-4 | lld:pubmed |
| pubmed-article:7660441 | pubmed:abstractText | With the emergence of widespread chloroquine resistance and a world-wide scarcity of quinine, a search for newer antimalarial drugs has become imperative. Different derivatives of qinghaosu have been successfully tried. alpha,beta-Arteether, an ethyl derivative of qinghaosu, was administered to 51 patients with Plasmodium falciparum malaria, in a dose of 150 mg intramuscularly once a day on 3 consecutive days. Complete parasite clearance from the peripheral blood was observed in 80% of the patients at 48 h and in 98% at 72 h. The median parasite clearance time was 2 d (range 1-4 d). 65% of the patients became afebrile within 48 h and 81% by 72 h. The mean fever clearance time was 52.04 h (standard deviation 27.09). No side effect was seen. Patients were followed-up for 4 weeks; 7 were readmitted with P. falciparum infection but it could not be ascertained definitely whether these cases were reinfections or recrudescences. alpha-beta Arteether was a safe, effective and convenient drug for treating P. falciparum malaria. This is the first clinical study with arteether in falciparum malaria. | lld:pubmed |
| pubmed-article:7660441 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7660441 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7660441 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7660441 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7660441 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7660441 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7660441 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7660441 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7660441 | pubmed:issn | 0035-9203 | lld:pubmed |
| pubmed-article:7660441 | pubmed:author | pubmed-author:DashSS | lld:pubmed |
| pubmed-article:7660441 | pubmed:author | pubmed-author:SrivastavaJ... | lld:pubmed |
| pubmed-article:7660441 | pubmed:author | pubmed-author:MohantySS | lld:pubmed |
| pubmed-article:7660441 | pubmed:author | pubmed-author:MishraS KSK | lld:pubmed |
| pubmed-article:7660441 | pubmed:author | pubmed-author:RathP KPK | lld:pubmed |
| pubmed-article:7660441 | pubmed:author | pubmed-author:DasB SBS | lld:pubmed |
| pubmed-article:7660441 | pubmed:author | pubmed-author:SatpathyS KSK | lld:pubmed |
| pubmed-article:7660441 | pubmed:author | pubmed-author:PatnaikJ KJK | lld:pubmed |
| pubmed-article:7660441 | pubmed:author | pubmed-author:AsthanaO POP | lld:pubmed |
| pubmed-article:7660441 | pubmed:author | pubmed-author:VargheseKK | lld:pubmed |
| pubmed-article:7660441 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7660441 | pubmed:volume | 89 | lld:pubmed |
| pubmed-article:7660441 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7660441 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7660441 | pubmed:pagination | 299-301 | lld:pubmed |
| pubmed-article:7660441 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:meshHeading | pubmed-meshheading:7660441-... | lld:pubmed |
| pubmed-article:7660441 | pubmed:articleTitle | Effectiveness of alpha,beta-arteether in acute falciparum malaria. | lld:pubmed |
| pubmed-article:7660441 | pubmed:affiliation | Department of Internal Medicine, Ispat General Hospital, Rourkela, Orissa, India. | lld:pubmed |
| pubmed-article:7660441 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7660441 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:7660441 | pubmed:publicationType | Clinical Trial, Phase II | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7660441 | lld:pubmed |
