| pubmed-article:7658061 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7658061 | lifeskim:mentions | umls-concept:C0025007 | lld:lifeskim |
| pubmed-article:7658061 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:7658061 | pubmed:dateCreated | 1995-10-4 | lld:pubmed |
| pubmed-article:7658061 | pubmed:abstractText | Live attenuated measles virus (MV) vaccines are ineffective in young infants because of neutralization by maternal antibody. An immunization strategy that may permit priming for T cell memory for MV in infants at or shortly after birth uses recombinant bacille Calmette-Guérin expressing the full-length MV nucleocapsid (N) protein (rBCG::N). C3H/He mice immunized with rBCG::N developed T cell responses and ELISA antibodies to the N protein and low levels of neutralizing antibody after intracranial infection with MV strain CAM/R40. There was considerable reduction in the virus titer recovered from brain homogenates, a decrease in the incidence and severity of histologic encephalitis, and a decrease in mortality in rBCG::N-printed C3H/He mice compared with control mice. Given the limitations of existing live attenuated MV vaccines, these results encourage the further testing of rBCG::N vaccines in primate models. | lld:pubmed |
| pubmed-article:7658061 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7658061 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7658061 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7658061 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7658061 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:7658061 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7658061 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:7658061 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7658061 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:7658061 | pubmed:issn | 0022-1899 | lld:pubmed |
| pubmed-article:7658061 | pubmed:author | pubmed-author:BloomB RBR | lld:pubmed |
| pubmed-article:7658061 | pubmed:author | pubmed-author:ter MeulenVV | lld:pubmed |
| pubmed-article:7658061 | pubmed:author | pubmed-author:LiebertU GUG | lld:pubmed |
| pubmed-article:7658061 | pubmed:author | pubmed-author:FlyntJ RJR | lld:pubmed |
| pubmed-article:7658061 | pubmed:author | pubmed-author:FennellyG JGJ | lld:pubmed |
| pubmed-article:7658061 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7658061 | pubmed:volume | 172 | lld:pubmed |
| pubmed-article:7658061 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7658061 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7658061 | pubmed:pagination | 698-705 | lld:pubmed |
| pubmed-article:7658061 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:7658061 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7658061 | pubmed:articleTitle | Recombinant bacille Calmette-Guérin priming against measles. | lld:pubmed |
| pubmed-article:7658061 | pubmed:affiliation | Department of Pediatrics, Albert Einstein College of Medicine, Bronx, New York 10461, USA. | lld:pubmed |
| pubmed-article:7658061 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7658061 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7658061 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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