| pubmed-article:7564036 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7564036 | lifeskim:mentions | umls-concept:C1186983 | lld:lifeskim |
| pubmed-article:7564036 | lifeskim:mentions | umls-concept:C0003280 | lld:lifeskim |
| pubmed-article:7564036 | lifeskim:mentions | umls-concept:C1306673 | lld:lifeskim |
| pubmed-article:7564036 | lifeskim:mentions | umls-concept:C0559956 | lld:lifeskim |
| pubmed-article:7564036 | lifeskim:mentions | umls-concept:C0237881 | lld:lifeskim |
| pubmed-article:7564036 | lifeskim:mentions | umls-concept:C0205195 | lld:lifeskim |
| pubmed-article:7564036 | lifeskim:mentions | umls-concept:C0750502 | lld:lifeskim |
| pubmed-article:7564036 | lifeskim:mentions | umls-concept:C1524063 | lld:lifeskim |
| pubmed-article:7564036 | lifeskim:mentions | umls-concept:C0085826 | lld:lifeskim |
| pubmed-article:7564036 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:7564036 | pubmed:dateCreated | 1995-11-14 | lld:pubmed |
| pubmed-article:7564036 | pubmed:abstractText | Patients who had undergone prosthetic valve replacement were treated with warfarin (anticoagulant) alone or in combination of ticlopidine (200 mg/day) or aspirin (81 mg/day) (anti-platelet agents). The study of blood coagulation factors and platelet aggregation were carried out with these cases. 1) The patients (n = 24) receiving warfarin for 21 days after prosthetic valve replacement revealed marked increases in PIVKA-II and vitamin K1-epoxide. The protein C activity was significantly lower than that before the operation. High levels of more than 5 ng/ml of TAT were found before operation and after warfarin administration for 21 days. 2) Warfarin did not affect platelet aggregation, whereas ticlopidine inhibited ADP-induced platelet aggregation and aspirin inhibited both collagen-induced and arachidonic acid-induced aggregation. In conclusion, combined use of anticoagulants and antiplatelet agents after prosthetic valve replacement will suppress not only the blood coagulation but also the platelet aggregation systems. | lld:pubmed |
| pubmed-article:7564036 | pubmed:language | jpn | lld:pubmed |
| pubmed-article:7564036 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7564036 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7564036 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7564036 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7564036 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7564036 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7564036 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7564036 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7564036 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:7564036 | pubmed:issn | 0021-5252 | lld:pubmed |
| pubmed-article:7564036 | pubmed:author | pubmed-author:YamadaKK | lld:pubmed |
| pubmed-article:7564036 | pubmed:author | pubmed-author:NakamuraKK | lld:pubmed |
| pubmed-article:7564036 | pubmed:author | pubmed-author:MoriyamaYY | lld:pubmed |
| pubmed-article:7564036 | pubmed:author | pubmed-author:TairaAA | lld:pubmed |
| pubmed-article:7564036 | pubmed:author | pubmed-author:ToyohiraHH | lld:pubmed |
| pubmed-article:7564036 | pubmed:author | pubmed-author:ShimokawaSS | lld:pubmed |
| pubmed-article:7564036 | pubmed:author | pubmed-author:KariyazonoHH | lld:pubmed |
| pubmed-article:7564036 | pubmed:author | pubmed-author:SaigenjiHH | lld:pubmed |
| pubmed-article:7564036 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7564036 | pubmed:volume | 48 | lld:pubmed |
| pubmed-article:7564036 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7564036 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7564036 | pubmed:pagination | 749-55 | lld:pubmed |
| pubmed-article:7564036 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
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| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:meshHeading | pubmed-meshheading:7564036-... | lld:pubmed |
| pubmed-article:7564036 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7564036 | pubmed:articleTitle | [Significance of combined use of anticoagulants and antiplatelet agents in the early stage after prosthetic valve replacement]. | lld:pubmed |
| pubmed-article:7564036 | pubmed:affiliation | Second Department of Surgery, Faculty of Medicine Kagoshima University, Japan. | lld:pubmed |
| pubmed-article:7564036 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7564036 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:7564036 | pubmed:publicationType | English Abstract | lld:pubmed |
| pubmed-article:7564036 | pubmed:publicationType | Controlled Clinical Trial | lld:pubmed |
