| pubmed-article:7536986 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7536986 | lifeskim:mentions | umls-concept:C0008051 | lld:lifeskim |
| pubmed-article:7536986 | lifeskim:mentions | umls-concept:C1321301 | lld:lifeskim |
| pubmed-article:7536986 | lifeskim:mentions | umls-concept:C0019630 | lld:lifeskim |
| pubmed-article:7536986 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:7536986 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:7536986 | pubmed:dateCreated | 1995-5-25 | lld:pubmed |
| pubmed-article:7536986 | pubmed:abstractText | Conditioned medium containing immune interferon (IFN) activity was prepared by stimulating spleen lymphocytes obtained from inbred SC chickens with 10 micrograms concanavalin A (Con A) for 48 h. Pretreatment of spleen cells with monoclonal antibody against CD4, but not CD8, abrogated IFN production suggesting that CD4+ lymphocytes are responsible for immune IFN production. Immune IFN was purified 25-fold from Con A conditioned medium using controlled-pore glass column chromatography resulting in an increase in specific antiviral activity from 7 to 3290 units mg-1. Partially purified immune IFN retained antiviral and macrophage-activating factor (MAF)-like activities. Normal peripheral blood macrophages, when cultured in the presence of partially purified immune IFN, showed a dose-dependent increase in cell surface major histocompatibility complex Class II antigen expression by flow cytometry. Northern blot analysis of mRNA obtained from IFN-treated macrophages showed a concomitant increase in Class II gene expression. This effect was more obvious in cells induced for 48 h than in those induced for 24 h. These results strongly suggest that existence of an avian homologue of the MAF-like activity. | lld:pubmed |
| pubmed-article:7536986 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7536986 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7536986 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7536986 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7536986 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7536986 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7536986 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7536986 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7536986 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7536986 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7536986 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:7536986 | pubmed:issn | 0165-2427 | lld:pubmed |
| pubmed-article:7536986 | pubmed:author | pubmed-author:LillehojH SHS | lld:pubmed |
| pubmed-article:7536986 | pubmed:author | pubmed-author:KaspersBB | lld:pubmed |
| pubmed-article:7536986 | pubmed:author | pubmed-author:JenkinsM CMC | lld:pubmed |
| pubmed-article:7536986 | pubmed:author | pubmed-author:PharrG TGT | lld:pubmed |
| pubmed-article:7536986 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7536986 | pubmed:volume | 44 | lld:pubmed |
| pubmed-article:7536986 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7536986 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7536986 | pubmed:pagination | 71-84 | lld:pubmed |
| pubmed-article:7536986 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7536986 | pubmed:meshHeading | pubmed-meshheading:7536986-... | lld:pubmed |
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| pubmed-article:7536986 | pubmed:meshHeading | pubmed-meshheading:7536986-... | lld:pubmed |
| pubmed-article:7536986 | pubmed:meshHeading | pubmed-meshheading:7536986-... | lld:pubmed |
| pubmed-article:7536986 | pubmed:meshHeading | pubmed-meshheading:7536986-... | lld:pubmed |
| pubmed-article:7536986 | pubmed:meshHeading | pubmed-meshheading:7536986-... | lld:pubmed |
| pubmed-article:7536986 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:7536986 | pubmed:articleTitle | Chicken interferon-mediated induction of major histocompatibility complex class II antigens on peripheral blood monocytes. | lld:pubmed |
| pubmed-article:7536986 | pubmed:affiliation | USDA, Beltsville Agricultural Research Center, MD 20705, USA. | lld:pubmed |
| pubmed-article:7536986 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7536986 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7536986 | lld:pubmed |
