pubmed-article:7509303 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7509303 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:7509303 | lifeskim:mentions | umls-concept:C0205147 | lld:lifeskim |
pubmed-article:7509303 | lifeskim:mentions | umls-concept:C0006556 | lld:lifeskim |
pubmed-article:7509303 | lifeskim:mentions | umls-concept:C0007428 | lld:lifeskim |
pubmed-article:7509303 | lifeskim:mentions | umls-concept:C0042333 | lld:lifeskim |
pubmed-article:7509303 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:7509303 | pubmed:dateCreated | 1994-3-25 | lld:pubmed |
pubmed-article:7509303 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7509303 | pubmed:abstractText | We have isolated two cathepsin B (CTSB)-encoding cDNAs, hCBF1 and hCBF2, from a normal human embryonic fibroblast library. These clones demonstrate 98% identity to overlapping regions of published human hepatoma and kidney CTSB cDNAs, but show some interesting differences from the published sequences in the 3'-untranslated region (3'-UTR). Both hCBF1 and hCBF2 contain a 10-bp insertion in the 3'-UTR that may permit formation of a highly stable stem-loop structure not present in mRNAs without this insertion. Our hCBF1 cDNA also contains a 1019-bp extension of the 3'-UTR sequence that resembles the long 3'-UTR reported for murine CTSB cDNAs. Probes unique to this 3'-UTR extension hybridize to 4.0- and 1.7-kb CTSB RNAs on Northern blots, but not to the major 2.2-kb mRNA transcript. Our data reveal variations in normal human CTSB transcripts that result from differences in the length of the 3'-UTR, as well as the presence or absence of a stem-loop stabilizing sequence. | lld:pubmed |
pubmed-article:7509303 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7509303 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7509303 | pubmed:language | eng | lld:pubmed |
pubmed-article:7509303 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7509303 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:7509303 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7509303 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7509303 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7509303 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7509303 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7509303 | pubmed:month | Feb | lld:pubmed |
pubmed-article:7509303 | pubmed:issn | 0378-1119 | lld:pubmed |
pubmed-article:7509303 | pubmed:author | pubmed-author:MurnaneM JMJ | lld:pubmed |
pubmed-article:7509303 | pubmed:author | pubmed-author:TamS WSW | lld:pubmed |
pubmed-article:7509303 | pubmed:author | pubmed-author:SheahanKK | lld:pubmed |
pubmed-article:7509303 | pubmed:author | pubmed-author:Cote-PaulinoL... | lld:pubmed |
pubmed-article:7509303 | pubmed:author | pubmed-author:PeakD ADA | lld:pubmed |
pubmed-article:7509303 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7509303 | pubmed:day | 25 | lld:pubmed |
pubmed-article:7509303 | pubmed:volume | 139 | lld:pubmed |
pubmed-article:7509303 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7509303 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7509303 | pubmed:pagination | 171-6 | lld:pubmed |
pubmed-article:7509303 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:7509303 | pubmed:meshHeading | pubmed-meshheading:7509303-... | lld:pubmed |
pubmed-article:7509303 | pubmed:meshHeading | pubmed-meshheading:7509303-... | lld:pubmed |
pubmed-article:7509303 | pubmed:meshHeading | pubmed-meshheading:7509303-... | lld:pubmed |
pubmed-article:7509303 | pubmed:meshHeading | pubmed-meshheading:7509303-... | lld:pubmed |
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pubmed-article:7509303 | pubmed:meshHeading | pubmed-meshheading:7509303-... | lld:pubmed |
pubmed-article:7509303 | pubmed:meshHeading | pubmed-meshheading:7509303-... | lld:pubmed |
pubmed-article:7509303 | pubmed:meshHeading | pubmed-meshheading:7509303-... | lld:pubmed |
pubmed-article:7509303 | pubmed:meshHeading | pubmed-meshheading:7509303-... | lld:pubmed |
pubmed-article:7509303 | pubmed:meshHeading | pubmed-meshheading:7509303-... | lld:pubmed |
pubmed-article:7509303 | pubmed:year | 1994 | lld:pubmed |
pubmed-article:7509303 | pubmed:articleTitle | Human cathepsin B-encoding cDNAs: sequence variations in the 3'-untranslated region. | lld:pubmed |
pubmed-article:7509303 | pubmed:affiliation | Department of Pathology, Boston University School of Medicine, MA 02118. | lld:pubmed |
pubmed-article:7509303 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7509303 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:7509303 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
entrez-gene:1508 | entrezgene:pubmed | pubmed-article:7509303 | lld:entrezgene |
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