| pubmed-article:7485268 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7485268 | lifeskim:mentions | umls-concept:C0012655 | lld:lifeskim |
| pubmed-article:7485268 | lifeskim:mentions | umls-concept:C0684224 | lld:lifeskim |
| pubmed-article:7485268 | lifeskim:mentions | umls-concept:C0700287 | lld:lifeskim |
| pubmed-article:7485268 | lifeskim:mentions | umls-concept:C0205147 | lld:lifeskim |
| pubmed-article:7485268 | lifeskim:mentions | umls-concept:C0001655 | lld:lifeskim |
| pubmed-article:7485268 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:7485268 | lifeskim:mentions | umls-concept:C0008660 | lld:lifeskim |
| pubmed-article:7485268 | lifeskim:mentions | umls-concept:C0005586 | lld:lifeskim |
| pubmed-article:7485268 | lifeskim:mentions | umls-concept:C0024779 | lld:lifeskim |
| pubmed-article:7485268 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:7485268 | pubmed:dateCreated | 1995-12-15 | lld:pubmed |
| pubmed-article:7485268 | pubmed:abstractText | We have examined the possible linkage of adrenocorticotropin receptor/melanocortin receptor-2 (ACTHR/MC-2) to a reported putative susceptibility locus for bipolar illness (BP) in 20 affected pedigrees. Initially, allelic variants of the gene were identified by polymerase chain reaction-single stranded conformation polymorphism (PCR-SSCP) and the gene was genetically mapped using both the Centre d'Etudes du Polymorphisme Humain (CEPH) pedigrees and the BP pedigrees used in this study. We found that the ACTHR/MC-2 gene maps between D18S53 and D18S66. These loci span a region of chromosome 18 which, in a previous study [Berrettini et al.: Proc Natl Acad Sci USA 91:5918-5921, 1994) revealed a putative predisposing locus to BP through nonparametric methods of linkage analysis. Linkage of ACTHR/MC-2 to BP was not demonstrable under parametric and nonparametric methods of analyses, although affected sib-pair (ASP) method revealed an increase in allele sharing among ill individuals, P = 0.023. Since this receptor is within a potential linkage region, ACTHR/MC-2 could be considered a candidate gene for BP. | lld:pubmed |
| pubmed-article:7485268 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7485268 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7485268 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7485268 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7485268 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7485268 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7485268 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7485268 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:7485268 | pubmed:issn | 0148-7299 | lld:pubmed |
| pubmed-article:7485268 | pubmed:author | pubmed-author:BerrettiniW... | lld:pubmed |
| pubmed-article:7485268 | pubmed:author | pubmed-author:TurnerGG | lld:pubmed |
| pubmed-article:7485268 | pubmed:author | pubmed-author:YoshikawaTT | lld:pubmed |
| pubmed-article:7485268 | pubmed:author | pubmed-author:GershonE SES | lld:pubmed |
| pubmed-article:7485268 | pubmed:author | pubmed-author:GoldinL RLR | lld:pubmed |
| pubmed-article:7485268 | pubmed:author | pubmed-author:YoonS WSW | lld:pubmed |
| pubmed-article:7485268 | pubmed:author | pubmed-author:NurnbergerJ... | lld:pubmed |
| pubmed-article:7485268 | pubmed:author | pubmed-author:Detera-Wadlei... | lld:pubmed |
| pubmed-article:7485268 | pubmed:author | pubmed-author:RollinsD YDY | lld:pubmed |
| pubmed-article:7485268 | pubmed:author | pubmed-author:MuniecDD | lld:pubmed |
| pubmed-article:7485268 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7485268 | pubmed:day | 14 | lld:pubmed |
| pubmed-article:7485268 | pubmed:volume | 60 | lld:pubmed |
| pubmed-article:7485268 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7485268 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7485268 | pubmed:pagination | 317-21 | lld:pubmed |
| pubmed-article:7485268 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:meshHeading | pubmed-meshheading:7485268-... | lld:pubmed |
| pubmed-article:7485268 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7485268 | pubmed:articleTitle | Adrenocorticotropin receptor/melanocortin receptor-2 maps within a reported susceptibility region for bipolar illness on chromosome 18. | lld:pubmed |
| pubmed-article:7485268 | pubmed:affiliation | Clinical Neurogenetics Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA. | lld:pubmed |
| pubmed-article:7485268 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7485268 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7485268 | lld:pubmed |
