pubmed-article:7410889 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7410889 | lifeskim:mentions | umls-concept:C0025684 | lld:lifeskim |
pubmed-article:7410889 | lifeskim:mentions | umls-concept:C0005507 | lld:lifeskim |
pubmed-article:7410889 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
pubmed-article:7410889 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
pubmed-article:7410889 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
pubmed-article:7410889 | lifeskim:mentions | umls-concept:C0392762 | lld:lifeskim |
pubmed-article:7410889 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:7410889 | pubmed:dateCreated | 1980-11-20 | lld:pubmed |
pubmed-article:7410889 | pubmed:abstractText | Photoactive 8-methoxypsoralen (8-MOP) levels in human and animal sera were determined by bioassay with Staphylcoccus aureus serving as the test organism. 8-MOP was extracted from sera with as 9:1 (V/V) ethyl acetate-n-hexane mixture and reconstituted in an aqueous medium following evaporation of the extractant. Bacterial suspensions containing extracted 8-MOP were irradiated for predetermined intervals with longwave ultraviolet light (UVA) at an intensity of 2.1 mw/cm2. Cultures containing known amounts of 8-MOP were used as standards and cytotoxicity (i.e., drug levels) determined by colony counts. The detection limit for 8-MOP was 5 ng/ml with an accuracy of +/- 10% above 10 ng/ml. Concomitant determinations of 8-MOP levels by high pressure liquid chromatography (HPLC) were in excellent agreement with the bioassay results. | lld:pubmed |
pubmed-article:7410889 | pubmed:language | eng | lld:pubmed |
pubmed-article:7410889 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7410889 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:7410889 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7410889 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7410889 | pubmed:month | Sep | lld:pubmed |
pubmed-article:7410889 | pubmed:issn | 0022-202X | lld:pubmed |
pubmed-article:7410889 | pubmed:author | pubmed-author:MalininG IGI | lld:pubmed |
pubmed-article:7410889 | pubmed:author | pubmed-author:GlewW BWB | lld:pubmed |
pubmed-article:7410889 | pubmed:author | pubmed-author:RobertsW PWP | lld:pubmed |
pubmed-article:7410889 | pubmed:author | pubmed-author:NigraT PTP | lld:pubmed |
pubmed-article:7410889 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7410889 | pubmed:volume | 75 | lld:pubmed |
pubmed-article:7410889 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7410889 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7410889 | pubmed:pagination | 230-4 | lld:pubmed |
pubmed-article:7410889 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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pubmed-article:7410889 | pubmed:year | 1980 | lld:pubmed |
pubmed-article:7410889 | pubmed:articleTitle | Quantitative determination by bioassay of photoactive 8-methoxypsoralen in serum. | lld:pubmed |
pubmed-article:7410889 | pubmed:publicationType | Journal Article | lld:pubmed |