pubmed-article:7232216 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7232216 | lifeskim:mentions | umls-concept:C0007090 | lld:lifeskim |
pubmed-article:7232216 | lifeskim:mentions | umls-concept:C0001011 | lld:lifeskim |
pubmed-article:7232216 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
pubmed-article:7232216 | lifeskim:mentions | umls-concept:C0205349 | lld:lifeskim |
pubmed-article:7232216 | lifeskim:mentions | umls-concept:C0071408 | lld:lifeskim |
pubmed-article:7232216 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:7232216 | pubmed:dateCreated | 1981-7-23 | lld:pubmed |
pubmed-article:7232216 | pubmed:abstractText | Poly (dG-dC) . poly(dG-dC) was modified by the reaction with N-acetoxy-N-acetyl-2-aminofluorene. The conformations of poly(dG-dC) . poly(dG-dC) and of poly d(G-C)AAF were studied by circular dichroism under various experimental conditions. In 95% ethanol, the two polynucleotides adopt the A-form. In 3.9 M LiCl, the transition B-form-C-form is observed with poly(dG-dC) . poly (dG-dC) but not with poly d(G-C)AAF. In 1 mM phosphate buffer, poly d(G-C)AAF behaves as a mixture of B- and Z-form, the relative percentages depending upon the amounts of modified bases. The percentage of Z-form is decreased by addition of EDTA and is increased by addition of Mg++. Spermine favors the Z-form in modified and unmodified polynucleotides. No defect in the double helix of poly d(G-C)AAF is detected by SI endonuclease. | lld:pubmed |
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pubmed-article:7232216 | pubmed:language | eng | lld:pubmed |
pubmed-article:7232216 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7232216 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:7232216 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7232216 | pubmed:month | Mar | lld:pubmed |
pubmed-article:7232216 | pubmed:issn | 0305-1048 | lld:pubmed |
pubmed-article:7232216 | pubmed:author | pubmed-author:LengMM | lld:pubmed |
pubmed-article:7232216 | pubmed:author | pubmed-author:SagiYY | lld:pubmed |
pubmed-article:7232216 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7232216 | pubmed:day | 11 | lld:pubmed |
pubmed-article:7232216 | pubmed:volume | 9 | lld:pubmed |
pubmed-article:7232216 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7232216 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7232216 | pubmed:pagination | 1241-50 | lld:pubmed |
pubmed-article:7232216 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:7232216 | pubmed:year | 1981 | lld:pubmed |
pubmed-article:7232216 | pubmed:articleTitle | Conformational changes of poly(dG-dC) . poly(dG-dC) modified by the carcinogen N-acetoxy-N-acetyl-2-aminofluorene. | lld:pubmed |
pubmed-article:7232216 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7232216 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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