| pubmed-article:7210711 | pubmed:abstractText | In 20 persons in old age and in 20 young persons the immunization with 0,5 ml of a vaccine (tetanus toxoid) was performed. The cell--immediated immunity of lymphocytes of these probands were investigated on the 0,7 21. and 28. day by lymphocyte-transformation test and E-rosette test. The boostering followed after 21 days with the same dose of the vaccine. It was found that the spontaneous transformation rate in T-lymphocytes in old age compared to the young age was duplicated. The stimulation with PHA (Phytämagglutinin) showed no significant differences while the specific cellular reactivity of the T-cells in old age is delayed and reduced compared to the T-cells in young age. | lld:pubmed |
