| pubmed-article:7190533 | pubmed:abstractText | Exercise was found to cause the release of 'extrinsic' plasminogen activators into the bloodstream. The 'intrinsic' plasma plasminogen activators were not significantly altered although factor VIII clotting activity and, to a lesser extent, its related antigen were both raised. A small amount of systemic fibrin(-ogen)olysis was indicated by the generation of fragment X and a slight reduction in the amount of intact A alpha-fibrinogen chain present. Plasminogen and antiplasmins were not significantly affected by exercise. We conclude that exercise-induced fibrinolysis is brought about solely by the release of plasminogen activators(s) from the vessel wall but that this enhanced level of fibrinolysis is insufficient to produce a marked degree of systemic fibrin(ogen) breakdown. | lld:pubmed |
