pubmed-article:6936873 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6936873 | lifeskim:mentions | umls-concept:C0017920 | lld:lifeskim |
pubmed-article:6936873 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
pubmed-article:6936873 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:6936873 | pubmed:dateCreated | 1981-4-21 | lld:pubmed |
pubmed-article:6936873 | pubmed:abstractText | Urinary excretion of the organic acids in patients with type I and III glycogenosis was investigated. In all patients with type I glycogenosis, urinary alpha-ketoglutarate concentration ws about 10 times the normal value. alpha-Ketoglutaric aciduria was not improved by the acute or prolonged administration of a large dose of factors for pyruvate- and alpha-ketoglutarate dehydrogenase complex. On the other hand, the level of alpha-ketoglutarate in the urine from type I patients decreased in conjunction with the decrease of plasma lactate and pyruvate concentration after repeated oral glucose loading. Oral citrate loading brought an increased excretion of alpha-ketoglutarate in type I glycogenosis. It is possible that alpha-ketoglutarate dehydrogenase in the rate-limiting step in tricarboxylic acid cycle and in patients with glycogenosis type I, the excessive excretion of alpha-ketoglutarate may be caused by the limited activity of alpha-ketoglutarate dehydrogenase with excessive substrate. | lld:pubmed |
pubmed-article:6936873 | pubmed:language | eng | lld:pubmed |
pubmed-article:6936873 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6936873 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6936873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6936873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6936873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6936873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6936873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6936873 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6936873 | pubmed:month | Aug | lld:pubmed |
pubmed-article:6936873 | pubmed:issn | 0040-8727 | lld:pubmed |
pubmed-article:6936873 | pubmed:author | pubmed-author:KodamaHH | lld:pubmed |
pubmed-article:6936873 | pubmed:author | pubmed-author:OkadaSS | lld:pubmed |
pubmed-article:6936873 | pubmed:author | pubmed-author:YutakaTT | lld:pubmed |
pubmed-article:6936873 | pubmed:author | pubmed-author:YabuuchiHH | lld:pubmed |
pubmed-article:6936873 | pubmed:author | pubmed-author:InuiKK | lld:pubmed |
pubmed-article:6936873 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6936873 | pubmed:volume | 131 | lld:pubmed |
pubmed-article:6936873 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6936873 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6936873 | pubmed:pagination | 347-53 | lld:pubmed |
pubmed-article:6936873 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:6936873 | pubmed:year | 1980 | lld:pubmed |
pubmed-article:6936873 | pubmed:articleTitle | Studies on alpha-ketoglutaric aciduria in type I glycogenosis. | lld:pubmed |
pubmed-article:6936873 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6936873 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |