| pubmed-article:69321 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:69321 | lifeskim:mentions | umls-concept:C0023473 | lld:lifeskim |
| pubmed-article:69321 | lifeskim:mentions | umls-concept:C0019721 | lld:lifeskim |
| pubmed-article:69321 | lifeskim:mentions | umls-concept:C0376249 | lld:lifeskim |
| pubmed-article:69321 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:69321 | pubmed:dateCreated | 1977-8-12 | lld:pubmed |
| pubmed-article:69321 | pubmed:abstractText | Histocompatibility antigen (HLA) phenotypes of 34 patients with Ph1+ chronic myelogenous leukemia (CML) were evaluated for association with HLA antigens. Two control populations were compared to the CML patients: 142 normal volunteer platelet donors, and 160 normal donors of granulocyte transfusions. HLA typing was done by lymphocyte microcytotoxicity tests for nine antigens on sublocus A and 15 antigens on sublocus B. HLA-B7 and HLA-B12 were decreased in CML patients compared to both platelet and granulocyte donors. There was increased frequency of HLA-A3 in patients (41%) as compared to controls (25% and 33%); HLA-B5 - patients = 20%; controls 8% and 6%; and HLA-BW17 - patients = 17%; controls = 6% and 3% (P = 0.01). Median survival was 24+ months and independent of HLA. HLA-B5 and HLA-BW17 were significantly increased in patients with CML compared to two normal control populations. No increase in HLA-B8 was seen. Decreased frequency of HLA-B7 and B12 was noted. The significance of these differences is being evaluated. | lld:pubmed |
| pubmed-article:69321 | pubmed:language | eng | lld:pubmed |
| pubmed-article:69321 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:69321 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:69321 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:69321 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:69321 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:69321 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:69321 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:69321 | pubmed:issn | 0038-4348 | lld:pubmed |
| pubmed-article:69321 | pubmed:author | pubmed-author:McCredieK BKB | lld:pubmed |
| pubmed-article:69321 | pubmed:author | pubmed-author:FreireichE... | lld:pubmed |
| pubmed-article:69321 | pubmed:author | pubmed-author:TrujilloJJ | lld:pubmed |
| pubmed-article:69321 | pubmed:author | pubmed-author:HesterJ PJP | lld:pubmed |
| pubmed-article:69321 | pubmed:author | pubmed-author:RossenRR | lld:pubmed |
| pubmed-article:69321 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:69321 | pubmed:volume | 70 | lld:pubmed |
| pubmed-article:69321 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:69321 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:69321 | pubmed:pagination | 691-3 | lld:pubmed |
| pubmed-article:69321 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-Hu... | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-Ch... | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-Le... | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-Fe... | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-Ma... | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-Te... | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-Ch... | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-Ep... | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-Ge... | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-Ch... | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-Hi... | lld:pubmed |
| pubmed-article:69321 | pubmed:meshHeading | pubmed-meshheading:69321-HL... | lld:pubmed |
| pubmed-article:69321 | pubmed:year | 1977 | lld:pubmed |
| pubmed-article:69321 | pubmed:articleTitle | Frequency of HLA antigens in chronic myelocytic leukemia. | lld:pubmed |
| pubmed-article:69321 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:69321 | lld:pubmed |
