pubmed-article:6863921 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6863921 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
pubmed-article:6863921 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
pubmed-article:6863921 | lifeskim:mentions | umls-concept:C0567416 | lld:lifeskim |
pubmed-article:6863921 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
pubmed-article:6863921 | lifeskim:mentions | umls-concept:C0031716 | lld:lifeskim |
pubmed-article:6863921 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
pubmed-article:6863921 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:6863921 | pubmed:dateCreated | 1983-8-11 | lld:pubmed |
pubmed-article:6863921 | pubmed:abstractText | Phosphorylcholine (PC), a molecule found in the cell wall of most serotypes of pneumococcus, has been used extensively as a probe for the study of network interactions during immune responses. The frequency of B lymphocytes capable of interacting with PC has not been directly examined. We used immunofluorescence to study the binding of PC and monoclonal anti-TEPC15 anti-idiotopic antibodies to murine lymphocytes. In addition to identifying PC-specific Ig molecules, PC was bound by a non-Ig molecule on the surface of a relatively large subset of B cells; this non-Ig marker shared an idiotypic determinant with the PC-binding myeloma protein HOPC8 (H8). PC-bearing R36a pneumococci bind to a similar subset of lymphocytes. This binding is inhibited specifically by PC coupled to bovine serum albumin and also by a monoclonal anti-H8 antibody. We suggest that bacterial interaction with B cells through non-Ig molecules capable of binding a dominant antigen like PC may possess functional significance, possibly during the events that lead to antibody induction by these microorganisms. | lld:pubmed |
pubmed-article:6863921 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6863921 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6863921 | pubmed:language | eng | lld:pubmed |
pubmed-article:6863921 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6863921 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:6863921 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6863921 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:6863921 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6863921 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6863921 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6863921 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6863921 | pubmed:month | Jul | lld:pubmed |
pubmed-article:6863921 | pubmed:issn | 0022-1767 | lld:pubmed |
pubmed-article:6863921 | pubmed:author | pubmed-author:KohlerHH | lld:pubmed |
pubmed-article:6863921 | pubmed:author | pubmed-author:LevittDD | lld:pubmed |
pubmed-article:6863921 | pubmed:author | pubmed-author:BachM AMA | lld:pubmed |
pubmed-article:6863921 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6863921 | pubmed:volume | 131 | lld:pubmed |
pubmed-article:6863921 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6863921 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6863921 | pubmed:pagination | 365-9 | lld:pubmed |
pubmed-article:6863921 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:6863921 | pubmed:year | 1983 | lld:pubmed |
pubmed-article:6863921 | pubmed:articleTitle | Binding of phosphorylcholine by non-immunoglobulin molecules on mouse B cells. | lld:pubmed |
pubmed-article:6863921 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6863921 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:6863921 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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