pubmed-article:6850341 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6850341 | lifeskim:mentions | umls-concept:C0085979 | lld:lifeskim |
pubmed-article:6850341 | lifeskim:mentions | umls-concept:C0027882 | lld:lifeskim |
pubmed-article:6850341 | lifeskim:mentions | umls-concept:C0012621 | lld:lifeskim |
pubmed-article:6850341 | lifeskim:mentions | umls-concept:C0019564 | lld:lifeskim |
pubmed-article:6850341 | lifeskim:mentions | umls-concept:C2349975 | lld:lifeskim |
pubmed-article:6850341 | lifeskim:mentions | umls-concept:C0599668 | lld:lifeskim |
pubmed-article:6850341 | lifeskim:mentions | umls-concept:C1627358 | lld:lifeskim |
pubmed-article:6850341 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:6850341 | pubmed:dateCreated | 1983-7-15 | lld:pubmed |
pubmed-article:6850341 | pubmed:abstractText | Acetylcholine (1-20 mM) was applied to guinea pig hippocampal slices bathed in normal and penicillin-containing media. Recordings in the CA 1 pyramidal cell layer in the presence of penicillin showed that acetylcholine caused a prolonged enhancement of the extracellular field potential. Intracellular recordings documented an increase in duration of cell bursting, a decrease in burst afterhyperpolarization, and a membrane depolarization lasting 1-5 min. These results suggest that the actions of acetylcholine to increase membrane excitability interact with penicillin-induced disinhibition to enhance hippocampal epileptogenesis. | lld:pubmed |
pubmed-article:6850341 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6850341 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6850341 | pubmed:language | eng | lld:pubmed |
pubmed-article:6850341 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6850341 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6850341 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6850341 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6850341 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6850341 | pubmed:month | Apr | lld:pubmed |
pubmed-article:6850341 | pubmed:issn | 0006-8993 | lld:pubmed |
pubmed-article:6850341 | pubmed:author | pubmed-author:PrinceD ADA | lld:pubmed |
pubmed-article:6850341 | pubmed:author | pubmed-author:KriegsteinA... | lld:pubmed |
pubmed-article:6850341 | pubmed:author | pubmed-author:SuppesTT | lld:pubmed |
pubmed-article:6850341 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6850341 | pubmed:day | 25 | lld:pubmed |
pubmed-article:6850341 | pubmed:volume | 266 | lld:pubmed |
pubmed-article:6850341 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6850341 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6850341 | pubmed:pagination | 137-42 | lld:pubmed |
pubmed-article:6850341 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:6850341 | pubmed:meshHeading | pubmed-meshheading:6850341-... | lld:pubmed |
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pubmed-article:6850341 | pubmed:meshHeading | pubmed-meshheading:6850341-... | lld:pubmed |
pubmed-article:6850341 | pubmed:year | 1983 | lld:pubmed |
pubmed-article:6850341 | pubmed:articleTitle | Cholinergic enhancement of penicillin-induced epileptiform discharges in pyramidal neurons of the guinea pig hippocampus. | lld:pubmed |
pubmed-article:6850341 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6850341 | pubmed:publicationType | In Vitro | lld:pubmed |
pubmed-article:6850341 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:6850341 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |