| pubmed-article:6747876 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6747876 | lifeskim:mentions | umls-concept:C0007450 | lld:lifeskim |
| pubmed-article:6747876 | lifeskim:mentions | umls-concept:C0228071 | lld:lifeskim |
| pubmed-article:6747876 | lifeskim:mentions | umls-concept:C0035298 | lld:lifeskim |
| pubmed-article:6747876 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:6747876 | lifeskim:mentions | umls-concept:C1709059 | lld:lifeskim |
| pubmed-article:6747876 | lifeskim:mentions | umls-concept:C1882911 | lld:lifeskim |
| pubmed-article:6747876 | pubmed:dateCreated | 1984-9-12 | lld:pubmed |
| pubmed-article:6747876 | pubmed:abstractText | The effects of applying the indoleamines serotonin (5-hydroxytryptamine) and 5-methoxy-N,N-dimethyltryptamine (MDT) ionophoretically onto cat retinal ganglion cells were studied in the optically intact eye of the cat. Serotonin suppressed both the spontaneous activity and light-evoked discharge of on-centre ganglion cells, regardless of the visual stimulus used; on the other hand, it enhanced the activity of off-centre ganglion cells. MDT produced the opposite effects, i.e. it enhanced the activity of on-centre ganglion cells but suppressed that of off-centre ganglion cells. Much of the effect of serotonin on light-evoked discharge can be attributed to an alteration of maintained discharge. There was no major difference in the way brisk-sustained (X) and brisk-transient (Y) cells responded to the application of serotonin and MDT, although the effects of the indoleamines on brisk-transient (Y) cells were generally weaker than on brisk-sustained (X) cells. In view of the fact that the action of serotonin is similar to the action of a gain control system, a possible contribution of indoleamine-accumulating neurones to gain control in the cat retina is discussed. | lld:pubmed |
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| pubmed-article:6747876 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6747876 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6747876 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6747876 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:6747876 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6747876 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:6747876 | pubmed:issn | 0022-3751 | lld:pubmed |
| pubmed-article:6747876 | pubmed:author | pubmed-author:WässleHH | lld:pubmed |
| pubmed-article:6747876 | pubmed:author | pubmed-author:ThierPP | lld:pubmed |
| pubmed-article:6747876 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6747876 | pubmed:volume | 351 | lld:pubmed |
| pubmed-article:6747876 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6747876 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6747876 | pubmed:pagination | 613-30 | lld:pubmed |
| pubmed-article:6747876 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6747876 | pubmed:meshHeading | pubmed-meshheading:6747876-... | lld:pubmed |
| pubmed-article:6747876 | pubmed:meshHeading | pubmed-meshheading:6747876-... | lld:pubmed |
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| pubmed-article:6747876 | pubmed:meshHeading | pubmed-meshheading:6747876-... | lld:pubmed |
| pubmed-article:6747876 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6747876 | pubmed:articleTitle | Indoleamine-mediated reciprocal modulation of on-centre and off-centre ganglion cell activity in the retina of the cat. | lld:pubmed |
| pubmed-article:6747876 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6747876 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6747876 | lld:pubmed |
