Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:6691859rdf:typepubmed:Citationlld:pubmed
pubmed-article:6691859lifeskim:mentionsumls-concept:C0086418lld:lifeskim
pubmed-article:6691859lifeskim:mentionsumls-concept:C0000768lld:lifeskim
pubmed-article:6691859lifeskim:mentionsumls-concept:C0205474lld:lifeskim
pubmed-article:6691859lifeskim:mentionsumls-concept:C0007303lld:lifeskim
pubmed-article:6691859lifeskim:mentionsumls-concept:C0311400lld:lifeskim
pubmed-article:6691859lifeskim:mentionsumls-concept:C0205307lld:lifeskim
pubmed-article:6691859pubmed:issue1lld:pubmed
pubmed-article:6691859pubmed:dateCreated1984-2-20lld:pubmed
pubmed-article:6691859pubmed:abstractTextIncorporation of radioactive precursors into macromolecules was studied with human normal and osteoarthritic articular cartilage organ culture. Analysis of the salt extracted matrix components separated by cesium chloride buoyant density gradient centrifugation showed an increase in the specific activities of all gradient fractions prepared from the osteoarthritic cartilage. Further analysis of these fractions showed the osteoarthritic cartilage contained 5 times as much sulfate incorporated into proteoglycans, and an even greater amount of 3H-glucosamine incorporated into material sedimenting to the middle of the gradient. Greater than half of this radioactive middle fraction appears to be hyaluronate, as judged by the position it elutes from a DEAE column and its susceptibility to hyaluronidase digestion. This study supports earlier findings showing increased rates of macromolecular synthesis in osteoarthritis, and in addition, an even greater synthetic rate for hyaluronic acid is demonstrated.lld:pubmed
pubmed-article:6691859pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:6691859pubmed:languageenglld:pubmed
pubmed-article:6691859pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:6691859pubmed:citationSubsetAIMlld:pubmed
pubmed-article:6691859pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:6691859pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:6691859pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:6691859pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:6691859pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:6691859pubmed:statusMEDLINElld:pubmed
pubmed-article:6691859pubmed:monthJanlld:pubmed
pubmed-article:6691859pubmed:issn0004-3591lld:pubmed
pubmed-article:6691859pubmed:authorpubmed-author:MankinH JHJlld:pubmed
pubmed-article:6691859pubmed:authorpubmed-author:TreadwellB...lld:pubmed
pubmed-article:6691859pubmed:authorpubmed-author:RyuJJlld:pubmed
pubmed-article:6691859pubmed:issnTypePrintlld:pubmed
pubmed-article:6691859pubmed:volume27lld:pubmed
pubmed-article:6691859pubmed:ownerNLMlld:pubmed
pubmed-article:6691859pubmed:authorsCompleteYlld:pubmed
pubmed-article:6691859pubmed:pagination49-57lld:pubmed
pubmed-article:6691859pubmed:dateRevised2007-11-14lld:pubmed
pubmed-article:6691859pubmed:meshHeadingpubmed-meshheading:6691859-...lld:pubmed
pubmed-article:6691859pubmed:meshHeadingpubmed-meshheading:6691859-...lld:pubmed
pubmed-article:6691859pubmed:meshHeadingpubmed-meshheading:6691859-...lld:pubmed
pubmed-article:6691859pubmed:meshHeadingpubmed-meshheading:6691859-...lld:pubmed
pubmed-article:6691859pubmed:meshHeadingpubmed-meshheading:6691859-...lld:pubmed
pubmed-article:6691859pubmed:meshHeadingpubmed-meshheading:6691859-...lld:pubmed
pubmed-article:6691859pubmed:meshHeadingpubmed-meshheading:6691859-...lld:pubmed
pubmed-article:6691859pubmed:meshHeadingpubmed-meshheading:6691859-...lld:pubmed
pubmed-article:6691859pubmed:meshHeadingpubmed-meshheading:6691859-...lld:pubmed
pubmed-article:6691859pubmed:meshHeadingpubmed-meshheading:6691859-...lld:pubmed
pubmed-article:6691859pubmed:year1984lld:pubmed
pubmed-article:6691859pubmed:articleTitleBiochemical and metabolic abnormalities in normal and osteoarthritic human articular cartilage.lld:pubmed
pubmed-article:6691859pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:6691859pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:6691859pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:6691859lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:6691859lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:6691859lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:6691859lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:6691859lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:6691859lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:6691859lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:6691859lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:6691859lld:pubmed