| pubmed-article:6577261 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6577261 | lifeskim:mentions | umls-concept:C0079337 | lld:lifeskim |
| pubmed-article:6577261 | lifeskim:mentions | umls-concept:C0314603 | lld:lifeskim |
| pubmed-article:6577261 | lifeskim:mentions | umls-concept:C0596988 | lld:lifeskim |
| pubmed-article:6577261 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:6577261 | lifeskim:mentions | umls-concept:C0205485 | lld:lifeskim |
| pubmed-article:6577261 | lifeskim:mentions | umls-concept:C1481605 | lld:lifeskim |
| pubmed-article:6577261 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:6577261 | pubmed:dateCreated | 1983-10-28 | lld:pubmed |
| pubmed-article:6577261 | pubmed:abstractText | R124 and R124/3 are R plasmids that carry the genes for two different restriction and modification systems. The phenotype of strains carrying either of these plasmids along with the F'lac+ plasmid, is restriction-deficient (Res-). The Res- phenotype is not due to selection of pre-existing mutants but rather to a complex mutational event caused by the F plasmid. Restriction-deficient mutants carry extensive deletions and other DNA rearrangements. Tn7 insertion is used to locate the restriction gene. Many of the Res- mutants are genetically unstable and revert at exceptionally high frequencies. Reversion is accompanied by DNA rearrangements which result in a net gain of 9 kb of DNA. F derivates of F+ which do not cause restriction-deficiency but do cause deletion were used to distinguish between the DNA rearrangements associated with restriction-deficiency and those associated with deletion. From Res+ revertants of strains carrying F'lac+ and R124 or R124/3 we have isolated F plasmids that now carry the genes for the R124 or R124/3 restriction and modification systems. It is suggested that interaction between part of the F plasmid and that segment of the R plasmid which controls the switch in Res-Mod specificity which has been observed (Glover et al. 1983) is responsible for the production of restriction-deficiency. | lld:pubmed |
| pubmed-article:6577261 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6577261 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6577261 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6577261 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6577261 | pubmed:issn | 0026-8925 | lld:pubmed |
| pubmed-article:6577261 | pubmed:author | pubmed-author:PriceCC | lld:pubmed |
| pubmed-article:6577261 | pubmed:author | pubmed-author:WatsonGG | lld:pubmed |
| pubmed-article:6577261 | pubmed:author | pubmed-author:CreaseyW AWA | lld:pubmed |
| pubmed-article:6577261 | pubmed:author | pubmed-author:GloverS WSW | lld:pubmed |
| pubmed-article:6577261 | pubmed:author | pubmed-author:FirmanKK | lld:pubmed |
| pubmed-article:6577261 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6577261 | pubmed:volume | 191 | lld:pubmed |
| pubmed-article:6577261 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6577261 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6577261 | pubmed:pagination | 145-53 | lld:pubmed |
| pubmed-article:6577261 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:6577261 | pubmed:meshHeading | pubmed-meshheading:6577261-... | lld:pubmed |
| pubmed-article:6577261 | pubmed:meshHeading | pubmed-meshheading:6577261-... | lld:pubmed |
| pubmed-article:6577261 | pubmed:meshHeading | pubmed-meshheading:6577261-... | lld:pubmed |
| pubmed-article:6577261 | pubmed:meshHeading | pubmed-meshheading:6577261-... | lld:pubmed |
| pubmed-article:6577261 | pubmed:meshHeading | pubmed-meshheading:6577261-... | lld:pubmed |
| pubmed-article:6577261 | pubmed:meshHeading | pubmed-meshheading:6577261-... | lld:pubmed |
| pubmed-article:6577261 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6577261 | pubmed:articleTitle | Genetic and physical studies of restriction-deficient mutants of the Inc FIV plasmids R124 and R124/3. | lld:pubmed |
| pubmed-article:6577261 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6577261 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6577261 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6577261 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6577261 | lld:pubmed |
