| pubmed-article:6520153 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6520153 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:6520153 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:6520153 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:6520153 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:6520153 | lifeskim:mentions | umls-concept:C0008565 | lld:lifeskim |
| pubmed-article:6520153 | lifeskim:mentions | umls-concept:C0085752 | lld:lifeskim |
| pubmed-article:6520153 | lifeskim:mentions | umls-concept:C0050885 | lld:lifeskim |
| pubmed-article:6520153 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:6520153 | pubmed:dateCreated | 1985-3-7 | lld:pubmed |
| pubmed-article:6520153 | pubmed:abstractText | A reversed-phase isocratic high-performance liquid chromatographic assay is described for the measurement of adriamycin, adriamycinol and their 7-deoxyaglycones in human serum. The lower limit of detection in serum is 3 ng/ml for adriamycin and 1 ng/ml for adriamycinol and the 7-deoxyaglycones with coefficients of variation for k' of less than 5% throughout the day. An extraction technique for serum is described which is capable of an almost equal recovery (greater than 77%) of adriamycin, metabolites and daunorubicin (the internal standard) without interference from endogenous components of serum. Serum concentrations of metabolites 15 min after intravenous bolus administration of 40 mg/m2 adriamycin in two different patients were 26.5 and 16.6 ng/ml for adriamycinol; 109.8 and 5.8 ng/ml for the adriamycinol 7-deoxyaglycone and 21.4 and 17.1 ng/ml for the adriamycin 7-deoxyaglycone. A total of six metabolites of adriamycin were detected in the two patients using this methodology. | lld:pubmed |
| pubmed-article:6520153 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6520153 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6520153 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6520153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6520153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6520153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6520153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6520153 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6520153 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:6520153 | pubmed:issn | 0021-9673 | lld:pubmed |
| pubmed-article:6520153 | pubmed:author | pubmed-author:CalmanK CKC | lld:pubmed |
| pubmed-article:6520153 | pubmed:author | pubmed-author:StuartJ FJF | lld:pubmed |
| pubmed-article:6520153 | pubmed:author | pubmed-author:CummingsJJ | lld:pubmed |
| pubmed-article:6520153 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6520153 | pubmed:day | 9 | lld:pubmed |
| pubmed-article:6520153 | pubmed:volume | 311 | lld:pubmed |
| pubmed-article:6520153 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6520153 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6520153 | pubmed:pagination | 125-33 | lld:pubmed |
| pubmed-article:6520153 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:6520153 | pubmed:meshHeading | pubmed-meshheading:6520153-... | lld:pubmed |
| pubmed-article:6520153 | pubmed:meshHeading | pubmed-meshheading:6520153-... | lld:pubmed |
| pubmed-article:6520153 | pubmed:meshHeading | pubmed-meshheading:6520153-... | lld:pubmed |
| pubmed-article:6520153 | pubmed:meshHeading | pubmed-meshheading:6520153-... | lld:pubmed |
| pubmed-article:6520153 | pubmed:meshHeading | pubmed-meshheading:6520153-... | lld:pubmed |
| pubmed-article:6520153 | pubmed:meshHeading | pubmed-meshheading:6520153-... | lld:pubmed |
| pubmed-article:6520153 | pubmed:meshHeading | pubmed-meshheading:6520153-... | lld:pubmed |
| pubmed-article:6520153 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6520153 | pubmed:articleTitle | Determination of adriamycin, adriamycinol and their 7-deoxyaglycones in human serum by high-performance liquid chromatography. | lld:pubmed |
| pubmed-article:6520153 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6520153 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6520153 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6520153 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6520153 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6520153 | lld:pubmed |
