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pubmed-article:6487464pubmed:abstractTextThe binding of propranolol enantiomers to human albumin (ALB), alpha 1-acid glycoprotein (alpha 1-AGP) and plasma was studied. (-) propranolol is more bound than (+)propranolol to alpha 1-AGP (P less than 0.001) and to plasma (P less than 0.05). In solutions containing ALB at a constant concentration (580 mumol/l) and alpha 1-AGP at increasing concentrations, the binding of both isomers increases but the stereo selectivity is evident throughout the alpha 1-AGP concentration range examined (25-100 mumol/l).lld:pubmed
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pubmed-article:6487464pubmed:articleTitleStereoselective binding of propranolol enantiomers to human alpha 1-acid glycoprotein and human plasma.lld:pubmed
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