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pubmed-article:6385380pubmed:abstractTextTo avoid nephrotoxicity and hepatotoxicity the CsA-PL should be kept at less than 500 ng/mL during the first month after transplantation and less than 200 ng/mL after four months. After ten months most patients in this study had a CsA-PL of less than 150 ng/mL and many had levels of less than 50 ng/mL with an apparently good immunosuppressive effect. Rejections showed no correlation with high or low CsA-PL. Continuous monitoring of CsA-PL is recommended for the management of renal allograft recipients.lld:pubmed
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pubmed-article:6385380pubmed:articleTitleOptimal cyclosporine plasma levels decline with time of therapy.lld:pubmed
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