| pubmed-article:6337097 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6337097 | lifeskim:mentions | umls-concept:C0038411 | lld:lifeskim |
| pubmed-article:6337097 | lifeskim:mentions | umls-concept:C0014597 | lld:lifeskim |
| pubmed-article:6337097 | lifeskim:mentions | umls-concept:C0016055 | lld:lifeskim |
| pubmed-article:6337097 | lifeskim:mentions | umls-concept:C0442027 | lld:lifeskim |
| pubmed-article:6337097 | lifeskim:mentions | umls-concept:C1510802 | lld:lifeskim |
| pubmed-article:6337097 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:6337097 | pubmed:dateCreated | 1983-3-24 | lld:pubmed |
| pubmed-article:6337097 | pubmed:abstractText | The possibility that fibronectin on the surface of oropharyngeal cells may serve as a receptor for the binding of group A streptococci (Streptococcus pyogenes) was investigated. Purified human plasma fibronectin inhibited the adherence of group A streptococci to oral epithelial cells in a dose-dependent manner. The relative amounts of fibronectin available on oral epithelial cells correlated closely with the ability of these cells to bind streptococci. Group A streptococci agglutinated latex beads containing covalently linked fibronectin on their surface, and this agglutination could be inhibited by lipoteichoic acid, the adhesion that mediates attachment of group A streptococci to epithelial cells. Gelatin and the alpha 1 chain of type I collagen partially inhibited both the adherence of streptococci to oral epithelial cells and the binding of radiolabeled fibronectin to streptococci; however, the purified fibronectin-binding peptide of collagen, alpha 1 (I)CB7, inhibited neither. The binding of radiolabeled fibronectin to streptococci was inhibited by lipoteichoic acid. These results suggest that fibronectin on oral epithelial cells serves as a lipoteichoic acid-sensitive receptor for group A streptococci. | lld:pubmed |
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| pubmed-article:6337097 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6337097 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6337097 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6337097 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6337097 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6337097 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:6337097 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:6337097 | pubmed:author | pubmed-author:BeacheyE HEH | lld:pubmed |
| pubmed-article:6337097 | pubmed:author | pubmed-author:SimpsonW AWA | lld:pubmed |
| pubmed-article:6337097 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6337097 | pubmed:volume | 39 | lld:pubmed |
| pubmed-article:6337097 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6337097 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6337097 | pubmed:pagination | 275-9 | lld:pubmed |
| pubmed-article:6337097 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6337097 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6337097 | pubmed:articleTitle | Adherence of group A streptococci to fibronectin on oral epithelial cells. | lld:pubmed |
| pubmed-article:6337097 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6337097 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6337097 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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