| pubmed-article:63345 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:63345 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
| pubmed-article:63345 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:63345 | lifeskim:mentions | umls-concept:C0037791 | lld:lifeskim |
| pubmed-article:63345 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:63345 | pubmed:dateCreated | 1977-2-16 | lld:pubmed |
| pubmed-article:63345 | pubmed:abstractText | Purified contractile proteins from smooth and striated muscles have been used to test the specificity of human smooth muscle antibodies (SMA) from patients with chronic liver disease (IgG-SMA) and acute hepatitis (IgM-SMA). The reactions, as detected by indirect immunofluorescence, of IgG-SMA with renal vessel walls, renal glomeruli, peritubular fibrils and the luminal part of the tubular cells could be completely abolished by absorption with either smooth muscle or skeletal muscle F-actin, while absorption with myosin and tropomyosin had no effect. The specificity of IgG-SMA for actin was confirmed by their staining of the actin-rich I-bands of skeletal muscle myofibrils and by the blocking of this reaction by pretreatment of myofibrils and isolated smooth muscle cells with smooth muscle myosin subfragment 1 (S-1). IgM-SMA from patients with acute hepatitis-stained renal vessel walls and some sera also stained renal glomeruli. The IgM-SMA titres decreased after absorption both with myosin and F-actin but not with tropomyosin. The reactivity of some IgM-SMA could be blocked by S-1 while others could not. Thus the specificity of IgM-SMA seemed to be variable, and apparently differed from IgG-SMA in some cases. | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:language | eng | lld:pubmed |
| pubmed-article:63345 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:63345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:63345 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:63345 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:63345 | pubmed:issn | 0009-9104 | lld:pubmed |
| pubmed-article:63345 | pubmed:author | pubmed-author:AndersenPP | lld:pubmed |
| pubmed-article:63345 | pubmed:author | pubmed-author:SobieszekAA | lld:pubmed |
| pubmed-article:63345 | pubmed:author | pubmed-author:SmallJ VJV | lld:pubmed |
| pubmed-article:63345 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:63345 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:63345 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:63345 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:63345 | pubmed:pagination | 57-66 | lld:pubmed |
| pubmed-article:63345 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Hu... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Mu... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Ki... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Li... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Ac... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-He... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Ab... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Mu... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Mu... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-An... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Ep... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Fl... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-My... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Im... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-Im... | lld:pubmed |
| pubmed-article:63345 | pubmed:meshHeading | pubmed-meshheading:63345-An... | lld:pubmed |
| pubmed-article:63345 | pubmed:year | 1976 | lld:pubmed |
| pubmed-article:63345 | pubmed:articleTitle | Studies on the specificity of smooth-muscle antibodies. | lld:pubmed |
| pubmed-article:63345 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:63345 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:63345 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:63345 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:63345 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:63345 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:63345 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:63345 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:63345 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:63345 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:63345 | lld:pubmed |
