| pubmed-article:6297892 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6297892 | lifeskim:mentions | umls-concept:C0736268 | lld:lifeskim |
| pubmed-article:6297892 | lifeskim:mentions | umls-concept:C1882726 | lld:lifeskim |
| pubmed-article:6297892 | lifeskim:mentions | umls-concept:C0205282 | lld:lifeskim |
| pubmed-article:6297892 | lifeskim:mentions | umls-concept:C0010531 | lld:lifeskim |
| pubmed-article:6297892 | lifeskim:mentions | umls-concept:C0022173 | lld:lifeskim |
| pubmed-article:6297892 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:6297892 | pubmed:dateCreated | 1983-4-15 | lld:pubmed |
| pubmed-article:6297892 | pubmed:abstractText | Total R proteins and total cAMP-dependent protein kinase activity during rat liver development reach highest values per unit DNA when the organ has attained full metabolic competence. The parallel changes indicate coordinate synthesis of R and C subunits during hepatic development. In contrast to total R2 . C2, protein kinase activation and endogenous cAMP levels were highest around birth. Immunotitration with anti-RI and anti-RII in the presence of protein-A-Sepharose of extracts obtained from various developmental stages and from hepatomas suggested a relation of both protein kinase I and II to the terminal differentiation of the organ rather than to cellular proliferation rates. The type-II enzyme appears to be subject to additional regulations connected with neonatal adaptation phenomena. A non-enzymic analysis of the protein kinase activation status is described. It is based on the determination of the ratio of amounts: R . cAMP/total R, which showed a linear correlation with the conventional protein kinase activity ratio (-cAMP/+cAMP). | lld:pubmed |
| pubmed-article:6297892 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6297892 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6297892 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6297892 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6297892 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6297892 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6297892 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6297892 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:6297892 | pubmed:issn | 0014-2956 | lld:pubmed |
| pubmed-article:6297892 | pubmed:author | pubmed-author:HilzHH | lld:pubmed |
| pubmed-article:6297892 | pubmed:author | pubmed-author:WeberWW | lld:pubmed |
| pubmed-article:6297892 | pubmed:author | pubmed-author:WittmaackF... | lld:pubmed |
| pubmed-article:6297892 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6297892 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:6297892 | pubmed:volume | 129 | lld:pubmed |
| pubmed-article:6297892 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6297892 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6297892 | pubmed:pagination | 669-74 | lld:pubmed |
| pubmed-article:6297892 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:6297892 | pubmed:meshHeading | pubmed-meshheading:6297892-... | lld:pubmed |
| pubmed-article:6297892 | pubmed:meshHeading | pubmed-meshheading:6297892-... | lld:pubmed |
| pubmed-article:6297892 | pubmed:meshHeading | pubmed-meshheading:6297892-... | lld:pubmed |
| pubmed-article:6297892 | pubmed:meshHeading | pubmed-meshheading:6297892-... | lld:pubmed |
| pubmed-article:6297892 | pubmed:meshHeading | pubmed-meshheading:6297892-... | lld:pubmed |
| pubmed-article:6297892 | pubmed:meshHeading | pubmed-meshheading:6297892-... | lld:pubmed |
| pubmed-article:6297892 | pubmed:meshHeading | pubmed-meshheading:6297892-... | lld:pubmed |
| pubmed-article:6297892 | pubmed:meshHeading | pubmed-meshheading:6297892-... | lld:pubmed |
| pubmed-article:6297892 | pubmed:meshHeading | pubmed-meshheading:6297892-... | lld:pubmed |
| pubmed-article:6297892 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6297892 | pubmed:articleTitle | Isoenzymes of cAMP-dependent protein kinase in developing rat liver and in malignant hepatic tissues. | lld:pubmed |
| pubmed-article:6297892 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6297892 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6297892 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6297892 | lld:pubmed |
