| pubmed-article:6260687 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6260687 | lifeskim:mentions | umls-concept:C0010247 | lld:lifeskim |
| pubmed-article:6260687 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:6260687 | lifeskim:mentions | umls-concept:C0037993 | lld:lifeskim |
| pubmed-article:6260687 | lifeskim:mentions | umls-concept:C0596402 | lld:lifeskim |
| pubmed-article:6260687 | lifeskim:mentions | umls-concept:C0439662 | lld:lifeskim |
| pubmed-article:6260687 | lifeskim:mentions | umls-concept:C1705241 | lld:lifeskim |
| pubmed-article:6260687 | lifeskim:mentions | umls-concept:C0449774 | lld:lifeskim |
| pubmed-article:6260687 | lifeskim:mentions | umls-concept:C1705242 | lld:lifeskim |
| pubmed-article:6260687 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:6260687 | pubmed:dateCreated | 1981-6-23 | lld:pubmed |
| pubmed-article:6260687 | pubmed:abstractText | Spleen cells from adult BALB/c mice injected intraperitoneally with purified coxsackievirus B-3 were tested for cytotoxicity against 51Cr-labeled syngeneic infected and uninfected myofibers. Both male and female immune cells were active against uninfected targets; this reactivity was evident by day 3 of infection and persisted throughout the first week. However, we observed marked sex-related differences in immune cell cytotoxicities against infected myofibers. Males exhibited a strong T-lymphocyte response 4 to 7 days after infection. In contrast, females exhibited a weak response, and only infrequently were the immune spleen cells of females significantly more reactive against infected myofibers than against uninfected myofibers. The demonstration of a stronger effector cell response against infected myocardial cells in male mice correlates with the observation that clinical adult coxsackievirus B myocarditis and pericarditis occur predominantly in males. | lld:pubmed |
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| pubmed-article:6260687 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6260687 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6260687 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:6260687 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6260687 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:6260687 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:6260687 | pubmed:author | pubmed-author:WoodruffJ FJF | lld:pubmed |
| pubmed-article:6260687 | pubmed:author | pubmed-author:HuberS ASA | lld:pubmed |
| pubmed-article:6260687 | pubmed:author | pubmed-author:LuiN SNS | lld:pubmed |
| pubmed-article:6260687 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6260687 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:6260687 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6260687 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6260687 | pubmed:pagination | 68-73 | lld:pubmed |
| pubmed-article:6260687 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6260687 | pubmed:year | 1981 | lld:pubmed |
| pubmed-article:6260687 | pubmed:articleTitle | Sex-related differences in the pattern of coxsackievirus B-3-induced immune spleen cell cytotoxicity against virus-infected myofibers. | lld:pubmed |
| pubmed-article:6260687 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6260687 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6260687 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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