pubmed-article:6208263 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6208263 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
pubmed-article:6208263 | lifeskim:mentions | umls-concept:C0178539 | lld:lifeskim |
pubmed-article:6208263 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
pubmed-article:6208263 | lifeskim:mentions | umls-concept:C0003261 | lld:lifeskim |
pubmed-article:6208263 | lifeskim:mentions | umls-concept:C1293122 | lld:lifeskim |
pubmed-article:6208263 | lifeskim:mentions | umls-concept:C1327458 | lld:lifeskim |
pubmed-article:6208263 | lifeskim:mentions | umls-concept:C1999177 | lld:lifeskim |
pubmed-article:6208263 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:6208263 | pubmed:dateCreated | 1984-12-19 | lld:pubmed |
pubmed-article:6208263 | pubmed:abstractText | We previously reported that B lymphocytes obtained from BALB/c mice that had been immunized with M104E myeloma protein have an idiotype-specific enhancing activity for anti-dextran B1355S antibody responses in vivo. The enhancing cells were Thy-1-, Lyt-1-,2-, nylon wool-adherent and rabbit anti-mouse immunoglobulin (RAMG) dish adherent. The in vitro analysis described in this report also revealed that the enhancing cells had a B cell phenotype and were specifically enriched in M104E or J558 myeloma protein-coated dishes but not by irrelevant monoclonal antibodies. The significance of these B-B cell interactions were analyzed in vitro by using various Igh-1 and H-2 congeneic strains of mice. The idiotype immune B lymphocytes obtained from BALB/c and BAB-14 could enhance the antidextran antibody responses of BALB/c B lymphocytes in an idiotype-specific manner. On the other hand, C.AL-20 and CB-20 strains could not induce the idiotype-specific enhancing B cell activity in dextran-immune BALB/c B cells. These results suggest that the capability of enhancing B cell induction is related to the producibility of the respective idiotype in that strain of mice. Moreover, the B cells obtained from BALB/c mice immune to the idiotype cooperated well with the dextran-immune B cells of BALB/c but not of BALB.K and vice versa. These results indicate that successful cooperation between those two types of B lymphocytes requires the same MHC haplotype. The roles of these genetically restricted cellular interactions in the immune system are discussed. | lld:pubmed |
pubmed-article:6208263 | pubmed:language | eng | lld:pubmed |
pubmed-article:6208263 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6208263 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:6208263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6208263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6208263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6208263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6208263 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6208263 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6208263 | pubmed:month | Dec | lld:pubmed |
pubmed-article:6208263 | pubmed:issn | 0022-1767 | lld:pubmed |
pubmed-article:6208263 | pubmed:author | pubmed-author:FujimotoSS | lld:pubmed |
pubmed-article:6208263 | pubmed:author | pubmed-author:YamamotoHH | lld:pubmed |
pubmed-article:6208263 | pubmed:author | pubmed-author:BitohSS | lld:pubmed |
pubmed-article:6208263 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6208263 | pubmed:volume | 133 | lld:pubmed |
pubmed-article:6208263 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6208263 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6208263 | pubmed:pagination | 2882-7 | lld:pubmed |
pubmed-article:6208263 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:6208263 | pubmed:year | 1984 | lld:pubmed |
pubmed-article:6208263 | pubmed:articleTitle | Regulation of immune responses via genetically-restricted cellular interactions. I. Augmentation of antibody responses by idiotype-specific enhancing B lymphocytes. | lld:pubmed |
pubmed-article:6208263 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6208263 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6208263 | lld:pubmed |