| pubmed-article:6182974 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6182974 | lifeskim:mentions | umls-concept:C2926606 | lld:lifeskim |
| pubmed-article:6182974 | lifeskim:mentions | umls-concept:C0684249 | lld:lifeskim |
| pubmed-article:6182974 | lifeskim:mentions | umls-concept:C0004398 | lld:lifeskim |
| pubmed-article:6182974 | lifeskim:mentions | umls-concept:C0262584 | lld:lifeskim |
| pubmed-article:6182974 | lifeskim:mentions | umls-concept:C0027627 | lld:lifeskim |
| pubmed-article:6182974 | lifeskim:mentions | umls-concept:C0524466 | lld:lifeskim |
| pubmed-article:6182974 | lifeskim:mentions | umls-concept:C2607943 | lld:lifeskim |
| pubmed-article:6182974 | lifeskim:mentions | umls-concept:C1707520 | lld:lifeskim |
| pubmed-article:6182974 | lifeskim:mentions | umls-concept:C0205210 | lld:lifeskim |
| pubmed-article:6182974 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:6182974 | pubmed:dateCreated | 1983-1-19 | lld:pubmed |
| pubmed-article:6182974 | pubmed:abstractText | Two hundred-twelve consecutive patients with small cell carcinoma of the lung were included in an evaluation of clinical and diagnostic neurologic findings of intracranial metastases. A correlation of premortem findings to postmortem examination of the brain was obtained in 87 of the patients. Clinical intracranial metastases were diagnosed in 21.2% on the basis of symptoms and signs. At autopsy 44 of the 87 patients (50%) had metastases. Lesions located to the posterior cranial fossa were demonstrated in 53% of the positive autopsies. A correlation of 96% existed between significant premortem clinical findings and positive autopsy, while 33% had clinically "silent" metastases at autopsy. A neuro-oncologic examination was performed in 49 patients at the time of presentation of neurologic symptoms. Twenty-eight patients were considered to have intracranial metastases. Gait disturbances were the presenting signs in more than 50% of the patients. Brain metastases were demonstrated at autopsy in 14 of 15 patients considered to have intracranial metastases by the neuro-oncologist, and clinically "silent" metastases were observed in one out of 10 patients. Radionuclide brain scan was negative in seven of 13 patients in spite of "positive" neuro-oncological examination had a subsequent positive autopsy. Cerebrospinal fluid examination was of no value in the diagnosis of brain metastases. It is concluded that a careful clinical examination by a neuro-oncologist is of great value in early detection of brain metastases, especially in diagnosing metastases to the posterior cranial fossa. | lld:pubmed |
| pubmed-article:6182974 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6182974 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6182974 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:6182974 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6182974 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6182974 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:6182974 | pubmed:issn | 0008-543X | lld:pubmed |
| pubmed-article:6182974 | pubmed:author | pubmed-author:HansenH HHH | lld:pubmed |
| pubmed-article:6182974 | pubmed:author | pubmed-author:PaulsonO BOB | lld:pubmed |
| pubmed-article:6182974 | pubmed:author | pubmed-author:Vraa-JensenJJ | lld:pubmed |
| pubmed-article:6182974 | pubmed:author | pubmed-author:HirschF RFR | lld:pubmed |
| pubmed-article:6182974 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6182974 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:6182974 | pubmed:volume | 50 | lld:pubmed |
| pubmed-article:6182974 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6182974 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6182974 | pubmed:pagination | 2433-7 | lld:pubmed |
| pubmed-article:6182974 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:6182974 | pubmed:meshHeading | pubmed-meshheading:6182974-... | lld:pubmed |
| pubmed-article:6182974 | pubmed:meshHeading | pubmed-meshheading:6182974-... | lld:pubmed |
| pubmed-article:6182974 | pubmed:meshHeading | pubmed-meshheading:6182974-... | lld:pubmed |
| pubmed-article:6182974 | pubmed:meshHeading | pubmed-meshheading:6182974-... | lld:pubmed |
| pubmed-article:6182974 | pubmed:meshHeading | pubmed-meshheading:6182974-... | lld:pubmed |
| pubmed-article:6182974 | pubmed:meshHeading | pubmed-meshheading:6182974-... | lld:pubmed |
| pubmed-article:6182974 | pubmed:meshHeading | pubmed-meshheading:6182974-... | lld:pubmed |
| pubmed-article:6182974 | pubmed:year | 1982 | lld:pubmed |
| pubmed-article:6182974 | pubmed:articleTitle | Intracranial metastases in small cell carcinoma of the lung: correlation of clinical and autopsy findings. | lld:pubmed |
| pubmed-article:6182974 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6182974 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6182974 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6182974 | lld:pubmed |
