| pubmed-article:6140139 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6140139 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:6140139 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:6140139 | lifeskim:mentions | umls-concept:C0005308 | lld:lifeskim |
| pubmed-article:6140139 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:6140139 | lifeskim:mentions | umls-concept:C0058372 | lld:lifeskim |
| pubmed-article:6140139 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:6140139 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:6140139 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:6140139 | pubmed:dateCreated | 1984-2-24 | lld:pubmed |
| pubmed-article:6140139 | pubmed:abstractText | The in vitro addition of betamethasone to rat liver microsomes caused a concentration-dependent stimulation of biphenyl 2-hydroxylation. At a 100 microM concentration of betamethasone, the formation of 2-hydroxybiphenyl was increased by approximately 4-fold in microsomes from 28-day-old rats and 10-fold in liver microsomes from 5-day-old rats. The steroid had little or no effect on the hydroxylation of biphenyl in the 3- or 4-position except at the highest concentration tested (1 mM), where a 20-30% inhibition was observed. The ip injection of 0.01 to 10 mumol of betamethasone to 5-day-old rats had little or no effect on the total body metabolism of 0.01 to 3.5 mumol of biphenyl-2-3H to 2-hydroxybiphenyl as measured by 3H2O formation. Although betamethasone had no effect on the 2-hydroxylation of biphenyl in the intact rat, this reaction was stimulated 4- to 9-fold by the addition of 100 microM betamethasone to hepatocyte monolayer cultures. | lld:pubmed |
| pubmed-article:6140139 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6140139 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6140139 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6140139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6140139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6140139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6140139 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6140139 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6140139 | pubmed:issn | 0090-9556 | lld:pubmed |
| pubmed-article:6140139 | pubmed:author | pubmed-author:ConneyA HAH | lld:pubmed |
| pubmed-article:6140139 | pubmed:author | pubmed-author:WilliamsG MGM | lld:pubmed |
| pubmed-article:6140139 | pubmed:author | pubmed-author:HuangM TMT | lld:pubmed |
| pubmed-article:6140139 | pubmed:author | pubmed-author:MillerM SMS | lld:pubmed |
| pubmed-article:6140139 | pubmed:author | pubmed-author:JeffreyA MAM | lld:pubmed |
| pubmed-article:6140139 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6140139 | pubmed:volume | 11 | lld:pubmed |
| pubmed-article:6140139 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6140139 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6140139 | pubmed:pagination | 556-61 | lld:pubmed |
| pubmed-article:6140139 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:6140139 | pubmed:meshHeading | pubmed-meshheading:6140139-... | lld:pubmed |
| pubmed-article:6140139 | pubmed:meshHeading | pubmed-meshheading:6140139-... | lld:pubmed |
| pubmed-article:6140139 | pubmed:meshHeading | pubmed-meshheading:6140139-... | lld:pubmed |
| pubmed-article:6140139 | pubmed:meshHeading | pubmed-meshheading:6140139-... | lld:pubmed |
| pubmed-article:6140139 | pubmed:meshHeading | pubmed-meshheading:6140139-... | lld:pubmed |
| pubmed-article:6140139 | pubmed:meshHeading | pubmed-meshheading:6140139-... | lld:pubmed |
| pubmed-article:6140139 | pubmed:meshHeading | pubmed-meshheading:6140139-... | lld:pubmed |
| pubmed-article:6140139 | pubmed:meshHeading | pubmed-meshheading:6140139-... | lld:pubmed |
| pubmed-article:6140139 | pubmed:meshHeading | pubmed-meshheading:6140139-... | lld:pubmed |
| pubmed-article:6140139 | pubmed:articleTitle | Effects of betamethasone on the in vitro and in vivo 2-hydroxylation of biphenyl in the rat. | lld:pubmed |
| pubmed-article:6140139 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6140139 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:6140139 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6140139 | lld:pubmed |
