| pubmed-article:455450 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:455450 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:455450 | lifeskim:mentions | umls-concept:C1516511 | lld:lifeskim |
| pubmed-article:455450 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:455450 | lifeskim:mentions | umls-concept:C0205369 | lld:lifeskim |
| pubmed-article:455450 | lifeskim:mentions | umls-concept:C0332453 | lld:lifeskim |
| pubmed-article:455450 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:455450 | pubmed:dateCreated | 1979-9-25 | lld:pubmed |
| pubmed-article:455450 | pubmed:abstractText | We have compared the chromatin structure in the active and inactive states at loci encoding the major heat shock protein in Drosophila. DNAase I and micrococcal nuclease were used as probes of higher order organization and nucleosomal integrity. Such integrity is gauged here by the characteristic pattern of discrete DNA fragments produced at specific chromosomal loci by nucleolytic cleavage. The specific fragment patterns are visualized by gel electrophoresis, Southern blotting onto nitrocellulose sheets, hybridization with 32P-labeled cloned DNA containing the heat shock genes and autoradiography. Using this criterion, a disruption in nucleosomal and possibly in higher order organization are observed as indicated by a relative loss or smearing of the characteristic discrete DNA fragment patterns from the heat shock loci in the active state. The fragment patterns are restored when cells are allowed to recover from heat shock and these loci return to the inactive state. | lld:pubmed |
| pubmed-article:455450 | pubmed:language | eng | lld:pubmed |
| pubmed-article:455450 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:455450 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:455450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:455450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:455450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:455450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:455450 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:455450 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:455450 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:455450 | pubmed:author | pubmed-author:WongY CYC | lld:pubmed |
| pubmed-article:455450 | pubmed:author | pubmed-author:WuCC | lld:pubmed |
| pubmed-article:455450 | pubmed:author | pubmed-author:ElginS CSC | lld:pubmed |
| pubmed-article:455450 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:455450 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:455450 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:455450 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:455450 | pubmed:pagination | 807-14 | lld:pubmed |
| pubmed-article:455450 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:455450 | pubmed:meshHeading | pubmed-meshheading:455450-A... | lld:pubmed |
| pubmed-article:455450 | pubmed:meshHeading | pubmed-meshheading:455450-H... | lld:pubmed |
| pubmed-article:455450 | pubmed:meshHeading | pubmed-meshheading:455450-D... | lld:pubmed |
| pubmed-article:455450 | pubmed:meshHeading | pubmed-meshheading:455450-G... | lld:pubmed |
| pubmed-article:455450 | pubmed:meshHeading | pubmed-meshheading:455450-C... | lld:pubmed |
| pubmed-article:455450 | pubmed:meshHeading | pubmed-meshheading:455450-C... | lld:pubmed |
| pubmed-article:455450 | pubmed:meshHeading | pubmed-meshheading:455450-D... | lld:pubmed |
| pubmed-article:455450 | pubmed:meshHeading | pubmed-meshheading:455450-M... | lld:pubmed |
| pubmed-article:455450 | pubmed:meshHeading | pubmed-meshheading:455450-N... | lld:pubmed |
| pubmed-article:455450 | pubmed:meshHeading | pubmed-meshheading:455450-D... | lld:pubmed |
| pubmed-article:455450 | pubmed:year | 1979 | lld:pubmed |
| pubmed-article:455450 | pubmed:articleTitle | The chromatin structure of specific genes: II. Disruption of chromatin structure during gene activity. | lld:pubmed |
| pubmed-article:455450 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:455450 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:455450 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:455450 | lld:pubmed |
