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pubmed-article:4321262pubmed:abstractTextA major polar metabolite of cholecalciferol (vitamin D(3)) obtained from chick intestines is over four times as effective as cholecalciferol and over two times as effective as 25-hydroxycholecalciferol in stimulating intestinal calcium transport 24 hours after administration. Following a considerable lag, cholecalciferol and its 25-hydroxy derivative produce a maximum stimulation of the transport response at 24 to 48 hours. The polar intestinal metabolite greatly shortens this lag, stimulating maximum calcium transport by 9 hours. At 9 hours this metabolite is at least 13 times as active as the parent cholecalciferol and as such is a likely candidate for the biologically active form of cholecalciferol in the intestine.lld:pubmed
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pubmed-article:4321262pubmed:articleTitleVitamin D: A cholecalciferol metabolite highly active in promoting intestinal calcium transport.lld:pubmed
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