| pubmed-article:4279765 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:4279765 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
| pubmed-article:4279765 | lifeskim:mentions | umls-concept:C0012739 | lld:lifeskim |
| pubmed-article:4279765 | lifeskim:mentions | umls-concept:C0014264 | lld:lifeskim |
| pubmed-article:4279765 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:4279765 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:4279765 | pubmed:dateCreated | 1975-3-10 | lld:pubmed |
| pubmed-article:4279765 | pubmed:abstractText | Endotoxin administered intravenously to a group of four calves resulted in disseminated intravascular coagulation. A sublethal dose of piromen, a commercially available Pseudomonas spp endotoxin, was used. Serial measurements of total plasma fibrinogen, soluble fibrin levels, ethanol gelation tests, protamine sulfate tests, fibrinogen-fibrin-related antigen (FR-antigen) and prothrombin and thrombin times were done.Initial depression of plasma fibrinogen with a nadir of about 40% of pre-endotoxin levels at eight to 11 hours post-endotoxin (+8 to +11 hours) followed by an overcompensation to 180% at +60 to +108 hours was shown. Soluble fibrin was demonstrated in plasma from +2 to +22 hours with a peak of 100-114 mg/100 ml at +4 to +9 hours. Positive plasma ethanol gelation and protamine sulfate tests, as well as the presence of serum FR-antigen, occurred consistently following endotoxin administration. Significant increases in prothrombin times (PT) from +4 to +40 hours and in thrombin times (TT) from +4 to +16 hours were demonstrated. The peak increase of PT at +8 to +10 hours was 180%. The peak increase of TT at +6 to +9 hours was 260-290%. | lld:pubmed |
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| pubmed-article:4279765 | pubmed:language | eng | lld:pubmed |
| pubmed-article:4279765 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:4279765 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:4279765 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:4279765 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:4279765 | pubmed:issn | 0008-4050 | lld:pubmed |
| pubmed-article:4279765 | pubmed:author | pubmed-author:ValliV EVE | lld:pubmed |
| pubmed-article:4279765 | pubmed:author | pubmed-author:ThomsonG WGW | lld:pubmed |
| pubmed-article:4279765 | pubmed:author | pubmed-author:McSherryB JBJ | lld:pubmed |
| pubmed-article:4279765 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:4279765 | pubmed:volume | 38 | lld:pubmed |
| pubmed-article:4279765 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:4279765 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:4279765 | pubmed:pagination | 457-66 | lld:pubmed |
| pubmed-article:4279765 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:4279765 | pubmed:year | 1974 | lld:pubmed |
| pubmed-article:4279765 | pubmed:articleTitle | Endotoxin induced disseminated intravascular coagulation in cattle. | lld:pubmed |
| pubmed-article:4279765 | pubmed:publicationType | Journal Article | lld:pubmed |
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