Linked Life Data

4192611

Source:http://linkedlifedata.com/resource/pubmed/id/4192611

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:4192611rdf:typepubmed:Citationlld:pubmed
pubmed-article:4192611lifeskim:mentionsumls-concept:C0014834lld:lifeskim
pubmed-article:4192611lifeskim:mentionsumls-concept:C0041536lld:lifeskim
pubmed-article:4192611lifeskim:mentionsumls-concept:C0542341lld:lifeskim
pubmed-article:4192611pubmed:issue3lld:pubmed
pubmed-article:4192611pubmed:dateCreated1970-7-24lld:pubmed
pubmed-article:4192611pubmed:abstractText1. The function of ubiquinone in Escherichia coli was studied by using whole cells and membrane preparations of normal E. coli and of a mutant lacking ubiquinone. 2. The mutant lacking ubiquinone, strain AN59 (Ubi(-)), when grown under aerobic conditions, gave an anaerobic type of growth yield and produced large quantities of lactic acid, indicating that ubiquinone plays a vital role in electron transport. 3. NADH and lactate oxidase activities in membranes from strain AN59 (Ubi(-)) were greatly impaired and activity was restored by the addition of ubiquinone (Q-1). 4. Comparison of the percentage reduction of flavin, cytochrome b(1) and cytochrome a(2) in the aerobic steady state in membranes from the normal strain (AN62) and strain AN59 (Ubi(-)) and the effect of respiratory inhibitors on these percentages in membranes from strain AN62 suggest that ubiquinone functions at more than one site in the electron-transport chain. 5. Membranes from strain AN62, in the absence of substrate, showed an electron-spin-resonance signal attributed to ubisemiquinone. The amount of reduced ubiquinone (50%) found after rapid solvent extraction is consistent with the existence of ubiquinone in membranes as a stabilized ubisemiquinone. 6. The effects of piericidin A on membranes from strain AN62 suggest that this inhibitor acts at the ubiquinone sites: thus inhibition of electron transport is reversed by ubiquinone (Q-1); the aerobic steady-state oxidation-reduction levels of flavins and cytochrome b(1) in the presence of the inhibitor are raised to values approximating those found in the membranes of strain AN59 (Ubi(-)); the inhibitor rapidly eliminates the electron-spin-resonance signal attributed to ubisemiquinone and allows slow oxidation of endogenous ubiquinol in the absence of substrate and prevents reduction of ubiquinone in the presence of substrate. It is concluded that piericidin A separates ubiquinone from the remainder of the electron-transport chain. 7. A scheme is proposed in which ubisemiquinone, complexed to an electron carrier, functions in at least two positions in the electron-transport sequence.lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:languageenglld:pubmed
pubmed-article:4192611pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:citationSubsetIMlld:pubmed
pubmed-article:4192611pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:4192611pubmed:statusMEDLINElld:pubmed
pubmed-article:4192611pubmed:monthAprlld:pubmed
pubmed-article:4192611pubmed:issn0264-6021lld:pubmed
pubmed-article:4192611pubmed:authorpubmed-author:SnoswellA MAMlld:pubmed
pubmed-article:4192611pubmed:authorpubmed-author:RAOS RSRlld:pubmed
pubmed-article:4192611pubmed:authorpubmed-author:GibsonFFlld:pubmed
pubmed-article:4192611pubmed:authorpubmed-author:HamiltonJ AJAlld:pubmed
pubmed-article:4192611pubmed:authorpubmed-author:NewtonN ANAlld:pubmed
pubmed-article:4192611pubmed:issnTypePrintlld:pubmed
pubmed-article:4192611pubmed:volume117lld:pubmed
pubmed-article:4192611pubmed:ownerNLMlld:pubmed
pubmed-article:4192611pubmed:authorsCompleteYlld:pubmed
pubmed-article:4192611pubmed:pagination551-62lld:pubmed
pubmed-article:4192611pubmed:dateRevised2009-11-18lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:meshHeadingpubmed-meshheading:4192611-...lld:pubmed
pubmed-article:4192611pubmed:year1970lld:pubmed
pubmed-article:4192611pubmed:articleTitleThe function of ubiquinone in Escherichia coli.lld:pubmed
pubmed-article:4192611pubmed:publicationTypeJournal Articlelld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:4192611lld:pubmed
More...