| pubmed-article:387393 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:387393 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:387393 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:387393 | lifeskim:mentions | umls-concept:C0039593 | lld:lifeskim |
| pubmed-article:387393 | lifeskim:mentions | umls-concept:C1834741 | lld:lifeskim |
| pubmed-article:387393 | pubmed:dateCreated | 1980-1-19 | lld:pubmed |
| pubmed-article:387393 | pubmed:abstractText | Tests for nondisjunction have been carried out in male and female mice. Ten-day fetal progeny of control and treated adults have been karyotyped to establish spontaneous and induced levels of aneuploidy. In males, the effects of 100 rad x-rays on type A spermatogonia and early primary spermatocytes, and the effects of Mitomycin C (2 mg/kg) on early primary spermatocytes, have been tested. The results show insensitivity of primary spermatocytes to both agents, but a 3.5-fold increase in nondisjunction following spermatogonial irradiation. In females, comparisons have been made between young controls, young x-rayed (5 rad), aged controls and aged x-rayed (5 rad) animals. The "ageing effect" on nondisjunction is observed, but too few fetuses have been analyzed to reach conclusions regarding enhancement of nondisjunction levels by low doses of x-rays. | lld:pubmed |
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| pubmed-article:387393 | pubmed:language | eng | lld:pubmed |
| pubmed-article:387393 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:387393 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:387393 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:387393 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:387393 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:387393 | pubmed:issn | 0091-6765 | lld:pubmed |
| pubmed-article:387393 | pubmed:author | pubmed-author:ChandleyA CAC | lld:pubmed |
| pubmed-article:387393 | pubmed:author | pubmed-author:SpeedR MRM | lld:pubmed |
| pubmed-article:387393 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:387393 | pubmed:volume | 31 | lld:pubmed |
| pubmed-article:387393 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:387393 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:387393 | pubmed:pagination | 123-9 | lld:pubmed |
| pubmed-article:387393 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:387393 | pubmed:year | 1979 | lld:pubmed |
| pubmed-article:387393 | pubmed:articleTitle | Testing for nondisjunction in the mouse. | lld:pubmed |
| pubmed-article:387393 | pubmed:publicationType | Journal Article | lld:pubmed |
