| pubmed-article:372482 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C0178539 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C0023810 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C1510811 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C0457784 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:372482 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:372482 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:372482 | pubmed:dateCreated | 1979-6-29 | lld:pubmed |
| pubmed-article:372482 | pubmed:abstractText | By employing primary cultures of purified spleen cells from lipopolysaccharide (LPS) responder (C3H/HeN or C57BL/10Sn) or nonresponder (C3H/HeJ or C57BL/10ScN) mice incubated with particulate antigen and LPS prepared by phenol-water extraction (Ph), we have presented evidence that both T cells and macrophages (MO) are required for LPS-induced adjuvanticity. First, MO derived from C3H/HeN spleen cells, when mixed with responder, C3H/HeN lymphocytes and Ph-LPS, elicited enhanced antibody responses to sheep erythrocytes (SRC) antigen, whereas lymphocytes from the nonresponder, C3H/HeJ mouse strain did not evoke this response. Similarly, purified T cells from C3H/HeN spleens, when cultured with responder, nu/nu spleen cells, and Ph-LPS yielded enhanced anti-TNP PFC responses; whereas, C3H/HeJ T cells did not potentiate immune responses when mixed with optimal concentrations of Ph-LPS. LPS prepared by butanol-water extraction elicited significant adjuvant effects with all cell combinations. Finally, purified responder T cells and MO enabled either responder or nonresponder B cells to elicit LPS potentiation. These data indicate that T cells and MO are controlling LPS-induced augmentation of B-cell responses. | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:language | eng | lld:pubmed |
| pubmed-article:372482 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:372482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:372482 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:372482 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:372482 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:372482 | pubmed:author | pubmed-author:FarrarJ JJJ | lld:pubmed |
| pubmed-article:372482 | pubmed:author | pubmed-author:RosenstreichD... | lld:pubmed |
| pubmed-article:372482 | pubmed:author | pubmed-author:MergenhagenS... | lld:pubmed |
| pubmed-article:372482 | pubmed:author | pubmed-author:McGheeJ RJR | lld:pubmed |
| pubmed-article:372482 | pubmed:author | pubmed-author:MichalekS MSM | lld:pubmed |
| pubmed-article:372482 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:372482 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:372482 | pubmed:volume | 149 | lld:pubmed |
| pubmed-article:372482 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:372482 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:372482 | pubmed:pagination | 793-807 | lld:pubmed |
| pubmed-article:372482 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-A... | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-M... | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-L... | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-M... | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-M... | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-C... | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-A... | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-A... | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-H... | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-T... | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-B... | lld:pubmed |
| pubmed-article:372482 | pubmed:meshHeading | pubmed-meshheading:372482-L... | lld:pubmed |
| pubmed-article:372482 | pubmed:year | 1979 | lld:pubmed |
| pubmed-article:372482 | pubmed:articleTitle | Cellular requirements for lipopolysaccharide adjuvanticity. A role for both T lymphocytes and macrophages for in vitro responses to particulate antigens. | lld:pubmed |
| pubmed-article:372482 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:372482 | lld:pubmed |
