| pubmed-article:3722052 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3722052 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3722052 | lifeskim:mentions | umls-concept:C0026845 | lld:lifeskim |
| pubmed-article:3722052 | lifeskim:mentions | umls-concept:C0001480 | lld:lifeskim |
| pubmed-article:3722052 | lifeskim:mentions | umls-concept:C0243127 | lld:lifeskim |
| pubmed-article:3722052 | lifeskim:mentions | umls-concept:C1521828 | lld:lifeskim |
| pubmed-article:3722052 | lifeskim:mentions | umls-concept:C0022205 | lld:lifeskim |
| pubmed-article:3722052 | lifeskim:mentions | umls-concept:C0443331 | lld:lifeskim |
| pubmed-article:3722052 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:3722052 | pubmed:dateCreated | 1986-8-18 | lld:pubmed |
| pubmed-article:3722052 | pubmed:abstractText | ATP turnover and glycolytic rates during isometric contraction in humans have been investigated. Subjects contracted the knee extensor muscles at two-thirds maximal voluntary force to fatigue (mean +/- SE, 53 +/- 4 s). Biopsies were obtained before and after exercise and analyzed for high-energy phosphates and glycogenolytic-glycolytic intermediates. Total ATP turnover was 190 +/- 7 mmol/kg dry muscle, whereas the average turnover rate was 3.7 +/- 0.2 mmol . kg dry muscle-1 . S-1. The average ATP turnover rate was positively correlated with the percentage of fast-twitch fibers in the postexercise biopsy (r = 0.71; P less than 0.05) and negatively correlated with contraction duration to fatigue (r = -0.88; P less than 0.05). At fatigue, phosphocreatine ranged from 1 to 11 mmol/kg dry muscle (86-99% depletion of value at rest), whereas lactate ranged from 59 to 101. The mean glycolytic rate was 0.83 +/- 0.05 mmol . kg dry muscle-1 . S-1 and was positively correlated with the rate of glucose 6-phosphate accumulation (r = 0.83; P less than 0.05). It is concluded that a major determinant of the ATP turnover rate is the muscle fiber composition, which is probably explained by a higher turnover rate in fast-twitch fibers; fatigue is more closely related to a low phosphocreatine content than to a high lactate content; and the increase in prephosphofructokinase intermediates is important for stimulating glycolysis during contraction. | lld:pubmed |
| pubmed-article:3722052 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3722052 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3722052 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3722052 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3722052 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3722052 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3722052 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3722052 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3722052 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:3722052 | pubmed:issn | 8750-7587 | lld:pubmed |
| pubmed-article:3722052 | pubmed:author | pubmed-author:SahlinKK | lld:pubmed |
| pubmed-article:3722052 | pubmed:author | pubmed-author:KatzAA | lld:pubmed |
| pubmed-article:3722052 | pubmed:author | pubmed-author:HenrikssonJJ | lld:pubmed |
| pubmed-article:3722052 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3722052 | pubmed:volume | 60 | lld:pubmed |
| pubmed-article:3722052 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3722052 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3722052 | pubmed:pagination | 1839-42 | lld:pubmed |
| pubmed-article:3722052 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3722052 | pubmed:meshHeading | pubmed-meshheading:3722052-... | lld:pubmed |
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| pubmed-article:3722052 | pubmed:meshHeading | pubmed-meshheading:3722052-... | lld:pubmed |
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| pubmed-article:3722052 | pubmed:meshHeading | pubmed-meshheading:3722052-... | lld:pubmed |
| pubmed-article:3722052 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3722052 | pubmed:articleTitle | Muscle ATP turnover rate during isometric contraction in humans. | lld:pubmed |
| pubmed-article:3722052 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3722052 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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