| pubmed-article:3654424 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3654424 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3654424 | lifeskim:mentions | umls-concept:C0242184 | lld:lifeskim |
| pubmed-article:3654424 | lifeskim:mentions | umls-concept:C0034937 | lld:lifeskim |
| pubmed-article:3654424 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:3654424 | pubmed:dateCreated | 1987-11-9 | lld:pubmed |
| pubmed-article:3654424 | pubmed:abstractText | The recruitment curves of the monosynaptic Hoffmann (H) reflex and of the direct motor (M) excitation of alpha-motor fibers of the posterior popliteal nerve were studied in seven human subjects in normoxic and hypoxic conditions at sea level. The amplitude of the H and M responses were determined from the computerized full-wave rectified and integrated surface electromyographic (EMG) signal derived from bipolar surface electrodes placed over the soleus muscle. Hypoxic exposure [end-tidal O2 fraction (FETO2) = 0.066 +/- 0.003 and end-tidal CO2 fraction (FETCO2) = 0.0504 +/- 0.001 (SE)] did not affect the maximal M (Mmax) response but decreased significantly (7%) the maximal H (Hmax) response. The Hmax/Mmax ratio decreased from 0.60 to 0.53. Furthermore, by fitting the rising phase of the recruitment curves of the H and M responses vs. stimulus intensity with linear regressions, hypoxia was found to produce a significant decrease of similar magnitude (6%) in the threshold of both the H and M responses with no change in slope. Using a constant stimulus strength eliciting an H response of half the maximum (H50%) of the control conditions, hypoxia resulted in a 50% increase in the amplitude of the H response within 12 min. These results suggest that the effects of hypoxia on the nervous system consist of a direct depolarizing action on the peripheral alpha-fibers and 1A sensory fibers and of a central effect on supraspinal structures affecting the spinal alpha-motoneurons. | lld:pubmed |
| pubmed-article:3654424 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3654424 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3654424 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3654424 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3654424 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:3654424 | pubmed:issn | 8750-7587 | lld:pubmed |
| pubmed-article:3654424 | pubmed:author | pubmed-author:WillerJ CJC | lld:pubmed |
| pubmed-article:3654424 | pubmed:author | pubmed-author:GautierHH | lld:pubmed |
| pubmed-article:3654424 | pubmed:author | pubmed-author:MiserocchiGG | lld:pubmed |
| pubmed-article:3654424 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3654424 | pubmed:volume | 63 | lld:pubmed |
| pubmed-article:3654424 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3654424 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3654424 | pubmed:pagination | 639-45 | lld:pubmed |
| pubmed-article:3654424 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:meshHeading | pubmed-meshheading:3654424-... | lld:pubmed |
| pubmed-article:3654424 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3654424 | pubmed:articleTitle | Hypoxia and monosynaptic reflexes in humans. | lld:pubmed |
| pubmed-article:3654424 | pubmed:affiliation | Laboratory of Clinical Neurophysiology, Faculté de Médecine Saint-Antoine, Paris, France. | lld:pubmed |
| pubmed-article:3654424 | pubmed:publicationType | Journal Article | lld:pubmed |
